Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Integrated payload and mission planning, phase 3. Volume 2: Logic/Methodology for preliminary grouping of spacelab and mixed cargo payloads [PDF]
The logic and methodology for a preliminary grouping of Spacelab and mixed-cargo payloads is proposed in a form that can be readily coded into a computer program by NASA.
Johnson, J. F., Rodgers, T. E.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Responses of a large herbivore to predation risk are modulated by intrinsic and extrinsic factors
EcospherePrey species can perceive and respond to spatiotemporal variation in predation risk to increase survival. In addition to adjusting spatial and temporal activity patterns to avoid predation, prey employ other antipredator behaviors, such as vigilance and ...
Michael S. Muthersbaugh +7 more
doaj +1 more source
Braid Groups are Linear Groups
Advances in Mathematics, 1996 Let \(B_n\) denote the braid group on \(n\) strings. \(B_2\) is infinite cyclic and hence is a linear group. It is well-known that \(B_3\) is also a linear group. But it has remained an open problem as to whether any other braid groups are linear.
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Clustering Methods for Electricity Consumers: An Empirical Study in Hvaler-Norway [PDF]
, 2016 The development of Smart Grid in Norway in specific and Europe/US in general will shortly lead to the availability of massive amount of fine-grained spatio-temporal consumption data from domestic households.
Dang-Ha, The-Hien +2 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Slow 5-cycles and their Special Properties Heard in World Music
Analytical Approaches to World MusicThis essay develops and applies a theoretical language for describing a special family of musical cycles that feature five elements at very slow tempos, with the aim of appreciating the listening experiences they afford.
John Roeder
doaj
Female participation increases and gender segregation. ESRI WP564, May 2017 [PDF]
, 2017 This article examines the impact of a large increase in female participation on occupational segregation. Increases in female participation may decrease occupational segregation if women enter male dominated sectors but may increase segregation if they ...
Keane, Claire +2 more
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