The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Correction: Hydroxypropyl methylcellulose stearoxy ether hydrogel loaded with aloe vera peel-derived extracellular vesicle mimetics promotes wound healing in diabetic mice. [PDF]
Wang J +13 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Impact of Perceptual Load and Distractors' Perceptual Grouping on Visual Search in ASD. [PDF]
Shen W, Huang Y, Zhang L, Fu S.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Domain-Specific Perceptual Grouping of Human Dyads: Evidence from Autistic Trait Profiles
Richards BE +4 more
europepmc +1 more source
Perceptual grouping can affect the online control of goal-directed hand movements. [PDF]
Crowe EM +4 more
europepmc +1 more source
Letter to the Editor: analysis of cost differences between comparing Percutaneous transforaminal endoscopic discectomy (PTED) and unilateral biportal endoscopy (UBE) in the treatment of lumbar disc herniation under diagnosis-related group (DRG) payment - a retrospective cohort study. [PDF]
Ji D, Huang M, Zhu J, Wang L.
europepmc +1 more source
A Metaheuristic Optimization Algorithm for Task Clustering in Collaborative Multi-Cluster Systems. [PDF]
Li M, Hao Y, Zhang H, Xu J.
europepmc +1 more source
Perceptual grouping, not covert attention, drives the connectedness effect in the ANS. [PDF]
Adriano A, Velde MV.
europepmc +1 more source

