Results 151 to 160 of about 2,197,327 (302)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Clean Power Players: Landing a Job in Clean Energy [PDF]

open access: yes, 2016
A new, first-of-its-kind guidebook by Environmental Entrepreneurs (E2) and the Natural Resources Defense Council (NRDC) offers practical, how-to advice for young people seeking careers in clean ...
David Murray
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

2009 Oregon Harvest Roundup [PDF]

open access: yes, 2009
This harvest report for the Oregon wine industry from 2009 discusses how yields were most plentiful in the Willamette Valley, with average crop loads in other regions of the state.
Oregon Wine Board
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Quantifying Eulerian Eddy Leakiness in an Idealized Model [PDF]

open access: yes, 2019
An idealized eddy‐resolving ocean basin, closely resembling the North Pacific Ocean, is simulated using MITgcm. We identify rotationally coherent Lagrangian vortices (RCLVs) and sea surface height (SSH) eddies based on the Lagrangian and Eulerian ...
Abernathey, Ryan   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Seed production in dianthus (Dianthus plumaris L.) : a thesis presented in partial fulfilment of the requirement for the degree of Master of Applied Science in Seed Technology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 1998
Stigma receptivity, method of pollination and seed production under glass house and field conditions of ten Hammett Dianthus (Dianthus plumaris L.) cultivars were investigated in this study.
Hewage, Nandana Pushpakumara
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Performance of Agronomic Crop Varieties in Alaska 1978 –2002 [PDF]

open access: yes, 2004
There is no such thing as the perfect variety for Alaska. Some varieties are adapted to a wide range of climatic and geographic locations, while others are more specific in their adaptation.
Knight, Charles W.   +1 more
core  

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