Results 181 to 190 of about 3,297,804 (232)

Mind the Gap: Rethinking Procedural Skill Assessment in Medical Residency. [PDF]

South Med J
Meliagros P, Garber A, Ambrosio M, Kang L, Forrest R.   +4 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Creation and Psychometric Validation of "Nursing Competencies Questionnaire on Older People's Environmental Health (NCQ-OPEH)" in Nurses and Nursing Students. [PDF]

Nurs Res Pract
Montoro-Ramírez EM, Parra-Anguita L, Álvarez-Nieto C, López-Medina IM.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Translation and validation of the Igbo version of the Warwick-Edinburgh Mental Well-being Scale in Nigeria. [PDF]

Int Health
Ekeke N, Ukwaja KN, Onyima-Esmai A, Ossai E, Chinawa F, Chukwu J, Nwafor C, Meka A, Egbule D, Obioma-Henry P, Njoku M, Eze C, Murphy-Okpala N.   +12 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Development and psychometric evaluation of the Spanish Cooking Self-Efficacy Questionnaire (SCSEQ) for Spanish University Students. [PDF]

PLoS One
Jurado-Gonzalez P, Medina FX, Martínez-Garcia A, López-Cediel Verdú A, Fàbregues S, Bach-Faig A.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Quantification of practice effects in a self-administered online cognitive pre-screening test. [PDF]

Neurol Sci
Wischmann HA, Huijbers W, Gillies M, Nasreddine Z.   +3 more
europepmc   +1 more source