Results 91 to 100 of about 19,782,958 (307)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This research is done on agriculture faculty’s land, University of Sumatera Utara, Medan (32 m asl) from Mei until August 2016 using factorial randomized block design with 2 treatment factor. The first factor is growing media with four type, soil (M1),
Dewantara, Fadhlan Rian
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The aim of this one semester course is to provide an introductory guide to important theoretical and methodological concerns that have influenced audience studies alongside some of the seminal work on the persuasive power of media.
Department of Media and Communications
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Growing old with and via media
What we understand at any given time as “old age” may seem to have a very straightforward and factual base. Yet, in the words of Simone de Beauvoir, “as far as our own species is concerned old age is by no means easy to define” (de Beauvoir, 1996, p. 9).
Mosberg Iversen, Sara +3 more
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Charter and by-laws of the Marienfeld Fruit Growing, Gardening and Irrigation Company
A pamphlet with the charter and bylaws of the Marienfeld Fruit Growing, Gardening and Irrigation ...
Marienfeld Fruit Growing, Gardening and Irrigation Company
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

