Results 161 to 170 of about 19,782,958 (307)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

PERTUMBUHAN MATA TUNAS JERUK KEPROK (CITRUS NOBILIS) HASIL OKULASI PADA BERBAGAI MEDIA TANAM DAN UMUR BATANG BAWAH ROUGH LEMON (C. JAMBHIRI)

Jurnal Ilmu Pertanian Indonesia, 2013
The objective of this study was to evaluate keprok (Citrus nobilis) budding seed development on various growing media and age of C. jambhiri rootstock. The design of experiment was complete randomized groups with 2 factors and 3 replications. The growing
Tatiek Kartika Suharsi, Ananda Dian Puspita Sari   +1 more
doaj  

Enseñanza media

, 2007
Debido al alcance y desarrollo que han logrado los estudios nocturnos para llevar la enseñanza media a la población trabajadora, se dispone el plan de actuación para el año académico 1966-1967, según informes de las Inspecciones de Enseñanza Media de los
Lora Tamayo, Manuel
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The effect of different growing media on the nutritional values and growing of edible flowers. [PDF]

BMC Plant Biol
Vural GY.
europepmc   +1 more source

Horticultural Growing Media and Plant Nutrition (b)

, 1998
The Effect of Planting Density on the Production Of Potato Minitubers Under Protection: Micropropagation of potatoes can be used to bulk up stocks of new cultivars or disease free stocks of existing cultivars. Rooted microplants are grown under protection to produce minitubers which undergo multiplication over a number of generations to produce seed ...
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Impact of Soilless Growing Media on Growth, Yield, Fruit Quality, and Root-Knot Nematode Incidence of Cucumber Under Protected Cultivation. [PDF]

Plant Environ Interact
Acharya SK, Patel GS, Yadav LP, Sahil A, Kaushik P, Meena NK, Mahala P, Khadivi A.   +7 more
europepmc   +1 more source