The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Beyond screen time: rethinking social media as a developmental context for adolescent well-being. [PDF]
Chaput JP, Sampasa-Kanyinga H.
europepmc +1 more source
Composted Agricultural and Forestry Organic Materials Amendment Rates Alter the Fluorescence Characteristics of WE-DOM and Chrysanthemum Growth in a Soil-Based Growing Medium. [PDF]
Li Y +8 more
europepmc +1 more source
Navigating Social Media: Balancing Connectivity With Media Literacy to Combat Misinformation and Protect Mental Well-Being. [PDF]
Al Musawi HK.
europepmc +1 more source
Translating JAH Science: Infographics for Enhanced Dissemination and Engagement in Adolescent Health Research. [PDF]
Hur JO +5 more
europepmc +1 more source
Mitigating the burden of dental caries among adolescents and young adults by targeting social media influencers. [PDF]
Shrivastava SR +3 more
europepmc +1 more source
Mechanical constraint causes lower turgor, thicker walls, and faster growth in Arabidopsis root hairs. [PDF]
Zambare V, Yi H, Anderson CT.
europepmc +1 more source

