Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
DNA Methylation Fine-Tunes Light- and Hormone-Responsive Growth Plasticity in <i>Arabidopsis</i> Seedlings. [PDF]
Talarico E +4 more
europepmc +1 more source
Evaluation of platelet-rich plasma from diabetic donors shows increased platelet vascular endothelial growth factor release [PDF]
Karina Karina +10 more
openalex +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Foliar Application of Some Amino Acids and Vitamins to Improve Growth, Physical and Chemical Properties of Flame Seedless Grapevines [PDF]
B Belal +66 more
openalex +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Self-aligned and self-limiting van der Waals epitaxy of monolayer MoS<sub>2</sub> for scalable 2D electronics. [PDF]
Sakuma Y +18 more
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Altered expression of metabolic pathways and immune-related genes revealed by RNA sequencing and metabolomic analysis in meat-type chickens with different growth rates. [PDF]
Ishihara S +4 more
europepmc +1 more source

