Results 251 to 260 of about 20,942,428 (379)

mTOR: from growth signal integration to cancer, diabetes and ageing

Nature reviews. Molecular cell biology, 2010
R. Zoncu, A. Efeyan, D. Sabatini
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

2005 Update of the Kennebunkport Comprehensive Plan [PDF]

, 2005
Kennebunkport (Me.). Growth Planning Committee
core   +1 more source

Impact of thermal fluctuations on phytoplankton: an experimental multi-trait analysis across species. [PDF]

J Plankton Res
Tascón-Peña O, Cabrerizo MJ, Pérez-Lorenzo M, Marañón E.   +3 more
europepmc   +1 more source

The Disorders of Post-natal Growth and Development

, 1911
H. Gilford
openalex   +2 more sources

The measurement of growth and deformation faulting in hexagonal cobalt [PDF]

, 1956
T. R. Anantharaman, J. W. Christian
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

2012 Kennebunkport Comprehensive Plan [PDF]

, 2012
Kennebunkport (Me.). Growth Planning Committee
core   +1 more source

Coastal seawater turbidity and thermal stress control growth of reef-building Porites spp. corals in Fiji. [PDF]

Sci Rep
Samperiz A, Sosdian S, Hendy E, Johnson K, John EH, Jupiter SD, Albert S.   +6 more
europepmc   +1 more source

p53, the Cellular Gatekeeper for Growth and Division

Cell, 1997
A. Levine
semanticscholar   +1 more source