Results 251 to 260 of about 23,882,396 (395)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Linear growth trajectories in the first two years of life predict attained linear growth and stunting at five years: Results from the MAL-ED multi-country birth cohort study. [PDF]

PLoS One
Alam MA, Hasan SMT, Nishan AA, Mahfuz M, Kosek MN, Lima AAM, Maciel BLL, Ahmed T.   +7 more
europepmc   +1 more source

Effect of a Fermentation Residue and an Antibiotic on Growth of Chickens Fed Rations Containing Corn or Wheat

, 1974
N.P. Johnston, G.H. Arscott
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Induction of colistin resistance and environmental toxicity assessment in Escherichia coli. [PDF]

PLoS One
Nunes Lima TH, de Souza M, Soares JM, Blanco KC, Salvador Bagnato EV.   +4 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Comparative liver proteome analysis of feedlot steer calves reveals growth trait-specific pathways influenced by calving season. [PDF]

J Anim Sci Biotechnol
Johnson C, Singh A, Hasan Z, Islam K, Yang Z, King M, Foote A, Lalman D, Ahsan N, Beck P.   +9 more
europepmc   +1 more source

National Survey of Family Growth, Cycle III, 1982

, 1982
United States Department of Health and Human Services. National Center for Health Statistics
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fluorescently engineered KRAS-mutant organoids as versatile tools for in vitro and in vivo cancer modeling. [PDF]

Biochem Biophys Rep
Savadipour A, Tummala KS, Muise ES, Buchanan M, Vidimar V, Veling M, Liu J, Kopinja J, Schneider C, Chan BPH, Carr R, Norton S, Gaspar JM, Piesvaux J, Leccese E, Park E, Moy LY, Long BJ, Solban N.   +18 more
europepmc   +1 more source