Results 101 to 110 of about 1,706,938 (308)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Pendapatan Akuntansi Dan Harga Saham Terhadap Pertumbuhan Dalam Produk Domistik Bruto (PDB)
The purpose of this research is to find out whether accounting income and stock prices can influence the movement of GDP growth. This study uses quantitative research methods, with up to 4 companies listed on the stock exchange using quarterly data from
Ahmad Junidi, Slamet Haryono
doaj
Accounting for Growth in Post-Soviet Russia [PDF]
In pursuit of its transition from a command to a market economy, post-Soviet Russia has witnessed enormous regional differences in economic growth rates.
Daniel Berkowitz and David N. DeJong +1 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
This study explores the role of corporate accounting earnings in predicting GDP growth at a macroeconomic level. It investigates whether negative aggregate accounting earnings are more effective predictors of GDP growth than positive earnings and how ...
Sari Atmini, Arum Prastiwi
doaj +1 more source
DETERMINANT ANALYSIS IN ACCOUNTING CONSERVATISM
This study aims to analyze the effect of managerial ownership structure, growth opportunities, leverage, and financial distress on accounting conservatism in manufacturing companies, especially the various industrial sectors and consumer goods in the ...
Wijayanti I. +2 more
doaj +1 more source
Infrastructure and economic growth in the Middle East and North Africa [PDF]
This paper analyzes the impact of infrastructure on growth of total factor productivity and per capita income, using both growth accounting techniques and cross-country growth regressions.
Straub, Stephane +2 more
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Política Fiscal, Choques de Oferta e a Expansão Econômica de 2003-2007
Este artigo possui dois objetivos. O primeiro é mostrar o impacto de impostos distorcivos sobre um período do ciclo econômico no Brasil. O segundo é mostrar que uma explicação para o crescimento do produto abaixo do crescimento da produtividade seria o ...
Roberto Ellery Jr, Victor Gomes
doaj
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source

