Results 121 to 130 of about 1,706,938 (308)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Accounting for Research and Productivity Growth Across Industries [PDF]
What factors underlie industry differences in research intensity and productivity growth? We develop a multi-sector endogenous growth model allowing for industry specific parameters in the production functions for output and knowledge, and in consumer ...
L. Rachel Ngai, Roberto M. Samaniego
core
Sources of Economic Growth: An Extensive Growth Accounting Exercise
IMF Staff Papers, 1999 A growth accounting exercise is conducted for 88 countries for 1960-94 to examine the source of cross-country differences in total factor productivity (TFP) levels. Two differences distinguish this analysis from that of the related literature. First, the critical technology parameter—the share of physical capital in real output—is econometrically ...
openaire +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
PRODUCTIVITY PROSOPOPOEIA IN GCC’S COUNTRIES: A GROWTH ACCOUNTING PERSPECTIVE. [PDF]
Annals of the University of Oradea: Economic Science, 2017 Through the past 16 years, the GCC region, testified swift changes such demographic, economic, and societal. GCC countries have taken important strides in economic development over the past, but it faces a number of challenges in the light of ...
Alshehhi Yahya
doaj
Accounting for Growth: Comparing China and India [PDF]
We compare the recent economic performances of China and India using a simple growth accounting framework that produces estimates of the contribution of labor, capital, education, and total factor productivity for the three sectors of agriculture ...
Barry Bosworth, Susan M. Collins
core
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Accounting Conservatism: Growth, Ownership, Distress, and Governance Interaction
Jurnal AkuntansiThis study examines the relationship between accounting conservatism in Indonesian non-financial firms and growth opportunity, managerial ownership, and financial distress, addressing conflicting findings in prior research and governance differences ...
Amanda Hermannisa, Badingatus Solikhah
doaj +1 more source
Revisiting productivity growth accounting decompositions
Research in EconomicsAbstract Productivity growth accounting decompositions are sensitive to the definition of aggregate productivity, which usually takes the form of a weighted geometric or arithmetic average of firms' productivities. This paper shows explicitly why the two differ.
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