Results 131 to 140 of about 9,743,245 (300)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Economic Growth in the Philippines: A Spatial Econometrics Analysis at the Provincial Level, 1991 – 2000. [PDF]

open access: yes
Investigating the determinants of economic growth remains a long research tradition in the economic growth literature. Most studies in this literature have tried to link economic growth and different economic factors using either neoclassical growth ...
Garcia, Cornelia   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The Export Growth of Pakistan: A Decomposition Analysis [PDF]

open access: yes
The Constant Market Share Analysis of export growth is used here to capture the world trade effect, the commodity composition effect, the market distribution effect and the competitiveness effect for the periods: 1984-85–1988-89 and 1988-89–1992-93.
Azhar Mahmood, Naeem Akhtar
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

GROWTH IN PARTIALLY DEFOLIATED STRAWBERRY PLANTS CULTIVATED IN THE TROPICAL HIGHLANDS CRECIMIENTO EN PLANTAS DE FRESA PARCIALMENTE DEFOLIADAS CULTIVADAS EN LOS ALTIPLANOS TROPICALES

open access: yesRevista U.D.C.A Actualidad & Divulgación Científica, 2012
Plants may undergo partial defoliation due to natural or accidental factors. The present study presents the results of an experiment to determine the effects of partial defoliation on the growth of strawberry plants (Fragaria X ananassa Duch.
Fánor Casierra-Posada   +2 more
doaj  

Trends and cycles in regional economic growth : how spatial differences formed the Swedish growth experience 1860-2009. [PDF]

open access: yes
Using a novel dataset on regional GDP per worker 1860-2009, this paper analyzes communalities in regional long-term growth trajectories for 24 Swedish provinces.
Andersson, Fredrik NG   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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