Results 121 to 130 of about 686,506 (262)

Tamaño óptimo de muestra para evaluar el patrón de crecimiento de frutos de naranjo 'Valencia late' Optimal sample size for evaluate the growth pattern of 'Valencia late' orange fruit

open access: yesRevista Brasileira de Fruticultura, 2010
Los modelos de crecimiento de frutos describen la evolución de su tamaño a lo largo del período de desarrollo. Con fines de pronóstico, estos modelos permiten estimar en forma anticipada el tamaño que alcanzarán los frutos al momento de la cosecha.
María Mercedes Avanza   +2 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Understanding orthopedic infections through a different perspective: Microcalorimetry growth curves. [PDF]

open access: yesExp Ther Med, 2022
Popa M   +9 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Growth curves for mandibular range of motion and maximum voluntary bite force in healthy children. [PDF]

open access: yesEur J Oral Sci, 2022
Verkouteren DRC   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

New Growth Curves for Spanish Children (0-10 Years) in the Region of Extremadura. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Pardo-Galán L   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

LOESS-Based Cephalometric Growth Curves for Clinical Assessment of Craniofacial Development: A Cross-Sectional Study. [PDF]

open access: yesDent J (Basel)
Cruz-Hervert LP   +11 more
europepmc   +1 more source

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