Results 161 to 170 of about 6,541,908 (257)

Decomposition of s - Concentration Curves [PDF]

For any given order of stochastic dominance, standard concentration curves are decomposed into contribution curves corresponding to within-group inequalities, between-group inequalities, and transvariational inequalities.
Paul Makdissi, Stéphane Mussard
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

LOESS-Based Cephalometric Growth Curves for Clinical Assessment of Craniofacial Development: A Cross-Sectional Study. [PDF]

Dent J (Basel)
Cruz-Hervert LP, Cruz-Chávez L, Kiseri-Kubati J, González-Aragón Pineda ÁE, Martínez-Suárez G, Ramírez-Martínez CM, Borges-Yañez SA, Solorio-Quezada JC, Trujillo-Sánchez MF, Martínez-Contreras SP, Jiménez-Corona ME, Jacinto-Alemán LF.   +11 more
europepmc   +1 more source

Growth Curves of Chinese Children with Androgen Insensitivity Syndrome: A Multicenter Registry Study. [PDF]

J Pers Med, 2022
Zhao X, Su Z, Chen S, Wang X, Yang Y, Chen L, Liang L, Liu G, Wang Y, Song Y, Fan L, Ren X, Gong C.   +12 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Time Series Data Mining for Linking the Shape of Bacterial Growth Curves to Biological Functions. [PDF]

Comput Struct Biotechnol J
Lao Z, Ying BW.
europepmc   +1 more source

Growth Curves and Body Condition of Young Cats and Their Relation to Maternal Body Condition. [PDF]

Animals (Basel), 2022
Opsomer H, Liesegang A, Brugger D, Wichert B.   +3 more
europepmc   +1 more source

Evaluating Different Growth Scenarios for Organic Farming Using Bayesian Techniques [PDF]

Different views exist on the future development of organic agriculture. The Dutch government believes that in 2010 10% of the farm land will be used for organic farming.
Gardebroek, Cornelis
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Fine Motor Development Growth Curves for Down Syndrome. [PDF]

J Child Neurol
Wiebers Jensen M, Wolf M, Feryn A, Nguyen T, Katlaps I, Pinter JD.   +5 more
europepmc   +1 more source