A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Real-World Effectiveness of DIMS Spectacle Lenses for Myopia Control in a Turkish Pediatric Population: A Retrospective Study Using Age-Specific Physiological Growth Curves. [PDF]
Akagun N, Altiparmak UE.
europepmc +1 more source
Speech Development Between 30 and 119 Months in Typical Children II: Articulation Rate Growth Curves. [PDF]
Mahr TJ +3 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Real-time fluorescence growth curves for viable bacteria quantification in foods. [PDF]
Chen Y, Chen Y, Tang S, Tang B, He S.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Investigation of growth curves with different nonlinear models and MARS algorithm in broiler chickens. [PDF]
Şengül T +4 more
europepmc +1 more source
sparse-growth-curve: a Computational Pipeline for Parsing Cellular Growth Curves with Low Temporal Resolution. [PDF]
Cheng C, Thrash JC.
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Centroid of the bacterial growth curves: a metric to assess phage efficiency. [PDF]
Hosseini N +3 more
europepmc +1 more source

