Results 281 to 290 of about 905,382 (336)

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

open access: yesAdvanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang   +13 more
wiley   +1 more source

Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis

open access: yesAdvanced Science, EarlyView.
This study develops RPTH by re‐modifying teriparatide and designs a biomimetic microstructured scaffold (BMRP) loaded with RPTH to address osteoporotic tendon‐to‐bone interface repair. The BMRP restores tissue architecture by balancing bone homeostasis and remodeling the microstructure, achieving functional recovery in an osteoporotic rotator cuff tear
Chengzhong Xu   +11 more
wiley   +1 more source

Morning vs. evening growth hormone injections and their impact on sleep-wake patterns and daytime alertness. [PDF]

open access: yesFront Endocrinol (Lausanne)
Levshtein A   +7 more
europepmc   +1 more source

Room‐Temperature Operable, Fully Recoverable Ethylene Gas Sensor via Pulsed Electric Field Modulation

open access: yesAdvanced Science, EarlyView.
Utilizing the electric field to regulate the electron behavior of sensing materials, a fast and complete recovery carbon‐based thin‐film transistor ethylene gas sensor is proposed. Abstract Ethylene (C2H4) is an important plant hormone, and its concentration can be used as an essential indicator of fruit quality. However, C2H4 is a non‐polar gas with a
Zeyu Zhang, Bolang Cheng, Yong Zhang
wiley   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan   +16 more
wiley   +1 more source

Empirical use of growth hormone in IVF is useless: the largest randomized controlled trial. [PDF]

open access: yesHum Reprod
Mourad A   +5 more
europepmc   +1 more source

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