Results 51 to 60 of about 3,405,715 (306)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

When is the growth index constant? [PDF]

Journal of Cosmology and Astroparticle Physics, 2016
The growth index $ $ is an interesting tool to assess the phenomenology of dark energy (DE) models, in particular of those beyond general relativity (GR). We investigate the possibility for DE models to allow for a constant $ $ during the entire matter and DE dominated stages.
Polarski, David, Starobinsky, Alexei A., Giacomini, Hector   +2 more
openaire   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Seed Treatments with Microorganisms Can Have a Biostimulant Effect by Influencing Germination and Seedling Growth of Crops

Plants, 2022
Seed quality is an important aspect of the modern cultivation strategies since uniform germination and high seedling vigor contribute to successful establishment and crop performance.
Mariateresa Cardarelli, Sheridan L. Woo, Youssef Rouphael, Giuseppe Colla   +3 more
doaj   +1 more source

Constraints on growth index parameters from current and future observations

, 2010
We use current and future simulated data of the growth rate of large scale structure in combination with data from supernova, BAO, and CMB surface measurements, in order to put constraints on the growth index parameters.
A. Albrecht ., A.G. Riess {., A.P. Lightman, Anzhong Wang, Cosmic acceleration initial observations\\ Supernova Search Team collaboration, D.J. Eisenstein, D.J. Eisenstein, E. Gaztañaga, ESSENCE collaboration, H.-J. Seo, HST collaboration, J.-Q. Xia, Jacob Moldenhauer, Jason Dossett, K. Koyama, L.-M. Wang, M. Hicken ., Mustapha Ishak, P.J.E. Peebles, R. Gannouji, S.M. Carroll, SDSS collaboration, SDSS collaboration, Supernova Cosmology Project collaboration, Supernova Cosmology Project collaboration, T.M. Davis ., W. Hu, W. Hu, WMAP collaboration, Yungui Gong   +29 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Reproductive Status of Larimichthys polyactis in Zhoushan Fishing Ground and Adjacent Waters from 2020 to 2021

Haiyang Kaifa yu guanli, 2022
In order to understand the reproductive characteristics of Larimichthys polyactis in Zhoushan fishing ground and surrounding waters, according to the trawl and barbed wire catch samples in Zhoushan fishing ground and adjacent waters from March to May in ...
Yali WANG, Cuilin HU, Kaida XU, Yongdong ZHOU, Rijin JIANG, Zhenhua LI, Xiafang LI   +6 more
doaj  

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Hand-Rearing of Three Lesser Flamingo Chicks (Phoeniconaias minor)

Animals, 2020
There are few published studies regarding lesser flamingo (Phoeniconaias minor) reproduction, crop milk composition, and hand-rearing under human care.
Letizia Fiorucci, Francesco Grande, Roberto Macrelli, Petra Schnitzer, Lorenzo Crosta   +4 more
doaj   +1 more source

THE APPLICATION OF AN INDEX TO DETERMINE GENETIC AND ENVIRONHENTAL CONTRIBUTIONS TO DENTOFACIAL GROWTH IN TWINS AND SIBLINGS [PDF]

, 1970
The method of principal components may be used to reduce a large quantity of data for an individual into a single statistic, a growth index, indicative of overall facial growth, and to make a determination of the relative contribution of each variable ...
Hayes, Richard Charles
core   +1 more source