Results 61 to 70 of about 450,220 (290)

Electric charging of dust aggregates and its effect on dust coagulation in protoplanetary disks

open access: yes, 2009
Mutual sticking of dust aggregates is the first step toward planetesimal formation in protoplanetary disks. In spite that the electric charging of dust particles is well recognized in some contexts, it has been largely ignored in the current modeling of ...
Blum   +22 more
core   +1 more source

Mathematical modeling of collagen turnover in biological tissue [PDF]

open access: yes, 2012
The final publication is available at Springer via http://dx.doi.org/10.1007/s00285-012-0613-yWe present a theoretical and computational model for collagen turnover in soft biological tissues. Driven by alterations in the mechanical environment, collagen
Kuhl, Ellen   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A Neural Network Approach for Mixing Language Models

open access: yes, 2017
The performance of Neural Network (NN)-based language models is steadily improving due to the emergence of new architectures, which are able to learn different natural language characteristics.
Klakow, Dietrich, Oualil, Youssef
core   +1 more source

The influence of anisotropic growth and geometry on the stress of solid tumors [PDF]

open access: yes, 2017
Solid stresses can affect tumor patho-physiology in at least two ways: directly, by compressing cancer and stromal cells, and indirectly, by deforming blood and lymphatic vessels.
Bravo-Castillero, Julián   +9 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

DigR : how to model root system in its environment? 1 - the model [PDF]

open access: yes, 2011
Many models already exist through literature dealing with root system representation, among which pure structure models such as Root Typ (Pagès 2004), SimRoot (Lynch 1997), AmapSim (Jourdan 1997); diffusion PDE models (Bastian 2008; Bonneu 2009) and ...
Barczi, Jean-François   +2 more
core  

Growth curve based on scale mixtures of skew-normal distributions to model the age-length relationship of Cardinalfish (Epigonus Crassicaudus)

open access: yes, 2012
Our article presents a robust and flexible statistical modeling for the growth curve associated to the age-length relationship of Cardinalfish (Epigonus Crassicaudus).
Arellano-Valle, Reinaldo B.   +1 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Psychopathological Risk During Adolescent Study-Abroad: A Larger-Cohort Update of a Previous Longitudinal Study

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
This article updates and extends a prior longitudinal study on adolescents’ psychological adjustment during short-term study-abroad programs, analyzing a newly collected larger cohort with the same design and measures. Using the same assessment schedule (
Silvia Cimino, Luca Cerniglia
doaj   +1 more source

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