Results 241 to 250 of about 7,577,606 (286)

Role of data-driven regional growth model in shaping brain folding patterns.

Soft Matter
Hou J, Wu Z, Chen X, Wang L, Zhu D, Liu T, Li G, Wang X.   +7 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

CA-based urban growth model considering the temporal dynamic adjustment of local spatial driving factors: An application in Wuhan City. [PDF]

Heliyon
Sun J, He Q, Wang H.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

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Modeling tumor growth

Mathematical Biosciences, 1991
The meaning and limitations of certain mathematical models of tumor growth are discussed, and some new derivations of the existing models are given. A theoretical justification for Gompertz's law of growth for tumors is presented. An age-dependent Von Bertalanffy's equation and diffusion models are introduced, and existence and uniqueness problems are ...
Calderón, Calixto P., Kwembe, Tor A.
openaire   +3 more sources

Plant Growth Models [PDF]

, 2008
This article attempts to describe the state of the art in building efficient dynamical plant growth and architecture models that contain the basic knowledge coming from botany, ecophysiology, agronomy, applied mathematics, and computer sciences. Plant architecture is the result of two processes working together: plant development, that concerns ...
de Reffye, Philippe, Heuvalick, E., Barthélémy, Daniel, Cournède, Paul-Henry   +3 more
openaire   +4 more sources