Results 181 to 190 of about 5,325,323 (353)

A nonconservative kinetic framework with logistic growth for modeling the coexistence in a multi-species ecological system

Marco Menale, Carmelo Filippo Munafò, Francesco Oliveri   +2 more
openalex   +1 more source

The Developmental Trajectory of Learned Helplessness in Breast Cancer Chemotherapy Patients: A Longitudinal Study Based on Latent Growth Models. [PDF]

Patient Prefer Adherence
Li X, Guo Z, Jiao Y, Lu Y, Ding S, Li X, Yang R, Chen C.   +7 more
europepmc   +1 more source

Comparison of Nonlinear Growth Models to Estimate Growth Curves in Kivircik Sheep under a Semi-Intensive Production System. [PDF]

Animals (Basel), 2023
Ozturk N, Kecici PD, Serva L, Ekiz B, Magrin L.   +4 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Inflation and output growth dynamics in South Africa: Evidence from the Markov switching vector auto-regression model [PDF]

, 2017
Lumengo Bonga‐Bonga, Beatrice D. Simo‐Kengne   +1 more
openalex  

On Discretely Structured Growth Models and Their Moments. [PDF]

Bull Math Biol
Walker BJ, Byrne HM.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Inverse Problem Regularization for 3D Multi-Species Tumor Growth Models. [PDF]

Int J Numer Method Biomed Eng
Ghafouri A, Biros G.
europepmc   +1 more source

Modelling epidemic growth models for lumpy skin disease cases in Thailand using nationwide outbreak data, 2021-2022. [PDF]

Infect Dis Model, 2023
Moonchai S, Himakalasa A, Rojsiraphisal T, Arjkumpa O, Panyasomboonying P, Kuatako N, Buamithup N, Punyapornwithaya V.   +7 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source