Results 121 to 130 of about 1,619,135 (319)

Effects of the interaction between tank color and type of feed pellets on biological and physiological indicators in red hybrid tilapia (Oreochromis mossambicus × Oreochromis niloticus) juveniles reared in brackish water

Journal of the World Aquaculture Society
The present work aimed to investigate the impacts of tank color (transparent, light blue, and red), feed pellet types (floating and sinking), and their interaction on the performance and welfare of red hybrid tilapia juveniles with an initial average ...
Ashraf Y. El‐Dakar, Shymaa M. Shalaby, Mohammed F. El Basuini, Mayada N. Atiya, Al‐Shaimaa M. Yakop, Elsayed M. Younis, Abdelwahab A. Abdelwarith, Simon J. Davies, Mohamed F. Abdel‐Aziz   +8 more
doaj   +1 more source

Parameter sensitivity of the ‘Limits to Growth’ world model

Applied Mathematical Modelling, 1976
Abstract The mathematical model basic to the results of ‘The Limits to Growth’ is found to be very sensitive to small parameter variations. By changing three parameters by 10% each in 1975 the world population collapse predicted by the model is averted.
Vermeulen, P. J., de Jongh, D. C. J.
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Efficient experimental designs for sigmoidal growth models [PDF]

For the Weibull- and Richards-regression model robust designs are determined by maximizing a minimum of D- or D1-efficiencies, taken over a certain range of the non-linear parameters.
Dette, Holger, Pepelyshev, Andrey
core  

Performance of artificial neural networks and traditional methods in determining selected growth parameters of Alburnus sellal Heckel, 1843

Oceanological and Hydrobiological Studies
In this study, predictions were made on the growth performance of Alburnus sellal Heckel, 1843 from the Munzur River using back propagation artificial neural networks and ANN algorithms. Statistical growth models used in fish biology and results obtained
Ozcan Ebru Ifakat
doaj   +1 more source

Why do lactic acid bacteria thrive in chain elongation microbiomes?

Frontiers in Bioengineering and Biotechnology
Efficient waste management is necessary to transition towards a more sustainable society. An emerging trend is to use mixed culture biotechnology to produce chemicals from organic waste.
Barbara Ulčar, Barbara Ulčar, Alberte Regueira, Alberte Regueira, Alberte Regueira, Maja Podojsteršek, Maja Podojsteršek, Nico Boon, Nico Boon, Ramon Ganigué, Ramon Ganigué   +10 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source