Results 181 to 190 of about 1,409,810 (317)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Growth performance and ultrasonographic body composition responses in lambs receiving Spirulina. [PDF]

Trop Anim Health Prod
Fahim NH, Elken EM, Othman MA, Saudi EM, El-Awady RM, Abdeltawab AS, Eldawy MH.   +6 more
europepmc   +1 more source

Growth performance in calves

Results on Growth performance in ...
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Internal audit quality, audit committee independence, growth opportunities and firm performance

, 2009
This study explores whether the relation between internal audit quality and firm performance is associated with firm characteristics of information asymmetry and uncertainty (growth opportunities) and certain governance controls (audit committee ...
Zain, Mazlina Mat, Hutchinson, Marion Ruth   +1 more
core  

Effect of Chrome Nanoparticle on Growth Performance, LiverTissue, and Oxidative Stress in Japanese Quails

In this study, the effects of adding different levels of chromium nanoparticles to quail feeds on growth performance and some blood and liver parameters of quails were examined.
Sema ALAŞAHAN, Tuncer KUTLU, ÖNEL, S. Ercüment, ALAŞAHAN, Sema, Şana SUNGUR, Altuğ KÜÇÜKGÜL, KUTLU, Tuncer, SUNGUR, Şana, KÜÇÜKGÜL, Altuğ, S. Ercüment ÖNEL   +9 more
core   +1 more source

Effects of Dietary Squalene Supplementation on the Growth Performance and Disease Resistance of Largemouth Bass. [PDF]

Vet Sci
Liu S, Chen M, Meng Y, Xue M, Zhou Y, Zhang L, Chen P, Fan Y, Yang Y, Huang Z.   +9 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Over a century of global decline in the growth performance of marine fishes. [PDF]

Nat Commun
Yan HF, Watkins HV, Siqueira AC, Bellwood DR.   +3 more
europepmc   +1 more source