<i>Trichoderma paratroviride</i> Strain 8942: Mechanisms of <i>Phytophthora infestans</i> Inhibition and Tomato Growth Promotion. [PDF]
J Fungi (Basel)Hu H +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Harnessing the multifunctional bioagent Streptomyces sp. SP5 for Fusarium wilt suppression, metabolite-mediated antioxidant activity, and plant growth promotion. [PDF]
Sci RepDevi S, Manhas RK.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Comparative genome analysis of Pseudomonas chlororaphis strains reveals biosynthetic diversity underlying plant growth promotion and soil health improvement. [PDF]
BMC GenomicsShahid I +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Metabolic Characteristics of PGPR-Induced Growth Promotion in Alfalfa (<i>Medicago sativa</i> L.). [PDF]
MetabolitesDao R, Zhang Y, Li Q, Lei S.
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Application potential of <i>Klebsiella pneumoniae</i> in agriculture: biodegradation, plant growth promotion, and alleviation of biotic and abiotic stresses. [PDF]
Open Life SciLiu D, Zhang B, Liu M, Song X, Chen J.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source