Results 101 to 110 of about 3,007,301 (314)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Productivity Growth and the Future of the U.S. Saving Rate [PDF]

open access: yes
consumption-income ratio; saving rate; medium-run; productivity growth; U.S.
Talan Iscan
core  

"The role of the exchange rate in economic growth: a euro-zone perspective" [PDF]

open access: yes, 2000
In this paper we consider a range of topics which connect exchange rates to the economic growth process. In particular, we first of all outline the basic properties of exchange rates when they are flexible.
Ronald MacDonald, MacDonald, Ronald
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Endogeneity of the Natural Rate of Growth: An Application to Turkey [PDF]

open access: yes
The purpose of this paper is to examine the sensitivity of the Turkish economy’s natural rate of growth to the actual rate of growth, covering the period 1980-2008.
Senay Acikgoz, Merter Mert
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Endogeneity of the Natural Rate of Growth – an Empirical Study for Latin-American Countries [PDF]

open access: yes
The aim of this paper is to analyse the sensitivity of the natural rate of growth to the actual rate of growth for a sample of eleven Latin-American countries, assuming the natural rate to be determined endogenously by changes in the actual rate of ...
Lena Vogel
core  

Environmental Consciousness, Economic Growth, and Macroeconomic Instability.

open access: yes, 2014
This paper develops an endogenous growth model to examine the linkages between environmental consciousness and economic growth. It is found that macroeconomic instability can arise in a simple AK-type growth model when the pollution externality is ...
Shieh, J. Y.; Chen, J. H.; Chang, S. H.; Lai, C. C.,   +1 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

FACTORS CONTRIBUTING IN GDP GROWTH RATE IN BANGLADESH

open access: yes, 2020
This analysis assesses the connection between per capita salaries, expansion rate, loan fee, FDI, global exchange, and monetary development rate in Bangladesh, by exploratory assessing dependable optional information of 2000 – 2019.
Mitu, Noshin Nawar
core  

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