Development of High Growth Rate SiC Epi-Reactor with Controlled Thermal Gradient
, 2007 M. Ito +3 more
openalex +1 more source
Phenotypic expression of resistance to penicillinase-stable beta-lactams in Staphylococcus aureus: growth rate, cross wall morphogenesis, and cell division cycle [PDF]
, 1982 F Rozgonyi
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The contribution rate of climate driven net primary productivity growth of vegetation has significantly increased, while human activities dominated its decrease from 1982 to 2020 in China [PDF]
Qi Chen, Wenjiao Shi, Wei Zhou
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
MOESM5 of Automated growth rate determination in high-throughput microbioreactor systems
, 2017 Johannes Hemmerich +2 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
HUMAN GROWTH HORMONE DOES NOT IMPROVE EUPLOIDY RATES PER OOCYTE RETRIEVED IN PATIENTS UNDERGOING IN VITRO FERTILIZATION WITH PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY [PDF]
Katherine Koniares +4 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source