Results 71 to 80 of about 2,611,689 (265)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Grow or die: A 49‐year growth history of a Japanese warm‐temperate tree species

Ecosphere
The growth trajectories of trees are not fully understood due to their long life span. We characterized the population dynamics of the canopy tree Castanopsis cuspidata (Thunb.) Schottky in a Japanese warm‐temperate forest over 49 years (1966–2015).
Toshihiro Yamada, Shin‐Ichiro Aiba, Kumiko Okubo, Eizi Suzuki, Hisayuki Maenaka, Masahiro Nagano, Yoshinori Nakajima, Toru Nagano, Masae Iwamoto Ishihara, Hiroki Yasumatsu, Yoshimi Sawada, Kazuyoshi Kawashima, Kunio Takami   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Natural History and Management of Ultrasound-detected Small Renal Angiomyolipoma

Journal of Medical Ultrasound
Background: Recent advances in imaging methods increased the incidental detection of small renal angiomyolipoma (AML). However, guidelines for managing small AML are lacking, and decisions about imaging frequency and timing of intervention are made on an
Minoru Kobayashi, Megumi Yokoyama, Hideo Yuki, Takao Kamai   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Weight and morphometric growth of different strains of tilapia (Oreochromis sp)

Revista Brasileira de Zootecnia, 2013
The objective of this study was to evaluate the morphometric growth and weight gain of strains of tilapia (Thai, Red, UFLA and Commercial) by nonlinear models.
Ivan Bezerra Allaman, Rafael Vilhena Reis Neto, Rilke Tadeu Fonseca de Freitas, Thiago Archangelo Freato, Aline de Assis Lago, Adriano Carvalho Costa, Renato Ribeiro de Lima   +6 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Red blood cell dynamics during malaria infection challenge the assumptions of mathematical models of infection dynamics

Frontiers in Malaria
For decades, mathematical models have been used to understand the course and outcome of malaria infections (i.e., infection dynamics) and the evolutionary dynamics of the parasites that cause them.
Madeline A. E. Peters, Madeline A. E. Peters, Madeline A. E. Peters, Aaron A. King, Aaron A. King, Aaron A. King, Aaron A. King, Nina Wale, Nina Wale, Nina Wale   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source