Results 141 to 150 of about 10,272,932 (259)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Semi-endogenous growth when population is decreasing [PDF]
The paper analyzes the effect of a negative population growth rate on per capita income growth using a simple model of semi-endogenous growth. It is shown that there is a non-monotonous relationship between population growth rates and long-run per capita
Thomas Christiaans
core
Growth rate of Engraulis mordax determined experimentally
, 2014 Growth rate of Engraulis mordax determined ...
Kimura, Makoto +3 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Topology and its Applications, 1991 Let \(K\) be an oriented \(n\)-knot with finitely generated commutator subgroup \(\pi_ 1'(K)\). The author defines the growth rate \(\gamma_ K\) of \(K\) in terms of the automorphism of \(\pi_ 1'(K)\) given by conjugation by a meridian. He shows that \(\gamma_ k\) is well-defined, and calculates the growth rate of a satellite knot in terms of the ...
openaire +1 more source
Words, deeds, and outcomes: A survey on the growth effects of exchange rate regimes [PDF]
Recent studies on the growth effects of exchange rate regimes offer a wide range of different, sometimes contradictory results. In this paper, we systematically compare three prominent contributions in this field.
Marco Kretschmann, Philipp Harms
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
The Size and Growth Rate of the Internet.
First Monday, 1998 The public Internet is currently far smaller, in both capacity and traffic, than the switched voice network. The private line networks are considerably larger in aggregate capacity than the Internet. They are about as large as the voice network in the U. S., but carry less traffic.
Coffman, Kerry, Odlyzko, Andrew
openaire +2 more sources