Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Growth rate controls the sensitivity of gene regulatory circuits. [PDF]
Julou T +3 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Nutrient Additions Regulate Height Growth Rate but Not Biomass Growth Rate of Alpine Plants Through the Contrasting Effect of Total and Available Nitrogen. [PDF]
Feng R +10 more
europepmc +1 more source
PD-L1 mRNA expression correlates with tumor growth rate in giant cell tumor of bone: a volumetric MRI analysis. [PDF]
Lee Y, Choi JY, Kim MJ, Seo SW.
europepmc +1 more source
Recent increase in N<sub>2</sub>O growth rate (2013-2023) mainly due to increase of nitrogen-fertiliser and manure use in the Northern Tropics and Southern Landmass. [PDF]
Patra PK +14 more
europepmc +1 more source
Predictors of retreatment after radiofrequency ablation of benign thyroid nodules: role of pre-treatment growth rate and viable volume. [PDF]
Ben Hamou A +5 more
europepmc +1 more source
Explaining the COVID19 mortality growth rate: an empirical analysis of Israeli cities. [PDF]
Arbel Y, Arbel Y, Kerner A, Kerner M.
europepmc +1 more source

