Results 201 to 210 of about 2,549,300 (265)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Enzymatic activity of PBP1B is required for growth rate-independent ppGpp-mediated resistance to PBP2 inhibitors in E. coli. [PDF]

J Bacteriol
Anderson SE, Mack IE, Levin PA.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Hemorrhagic transformation after endovascular treatment: Baseline infarct volume is a better predictor than infarct growth rate. [PDF]

Eur Stroke J
Méot M, Munsch F, Lapergue B, Kyheng M, Sibon I, Planes D, Micard E, Chen B, Olivot JM, Boulouis G, Viguier A, Tourdias T, Marnat G.   +12 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Nutrient Additions Regulate Height Growth Rate but Not Biomass Growth Rate of Alpine Plants Through the Contrasting Effect of Total and Available Nitrogen. [PDF]

Plants (Basel)
Feng R, Wang S, Ma J, Wang N, Wang X, Ren F, Li H, Liang D, Hu J, Li X, Li L.   +10 more
europepmc   +1 more source

Explaining the COVID19 mortality growth rate: an empirical analysis of Israeli cities. [PDF]

Front Public Health
Arbel Y, Arbel Y, Kerner A, Kerner M.
europepmc   +1 more source

PD-L1 mRNA expression correlates with tumor growth rate in giant cell tumor of bone: a volumetric MRI analysis. [PDF]

BMC Musculoskelet Disord
Lee Y, Choi JY, Kim MJ, Seo SW.
europepmc   +1 more source

A Comprehensive Analysis of the Abdominal Aortic Aneurysm Growth Rate in the Spanish Population. [PDF]

J Clin Med
Peypoch O, Calsina Juscafresa L, Vega-Méndez A, Lobato-Delgado B, Fité J, Soto B, Nieto L, de la Rosa Estadella M, Uribezubia A, Romero JM, Plana E, Miralles M, Clarà A, Dilmé J, Soria JM, Camacho M, Martinez-Perez A, Sabater-Lleal M.   +17 more
europepmc   +1 more source