Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Enzymatic activity of PBP1B is required for growth rate-independent ppGpp-mediated resistance to PBP2 inhibitors in E. coli. [PDF]
Anderson SE, Mack IE, Levin PA.
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Nutrient Additions Regulate Height Growth Rate but Not Biomass Growth Rate of Alpine Plants Through the Contrasting Effect of Total and Available Nitrogen. [PDF]
Feng R +10 more
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Hemorrhagic transformation after endovascular treatment: Baseline infarct volume is a better predictor than infarct growth rate. [PDF]
Méot M +12 more
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Explaining the COVID19 mortality growth rate: an empirical analysis of Israeli cities. [PDF]
Arbel Y, Arbel Y, Kerner A, Kerner M.
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A Comprehensive Analysis of the Abdominal Aortic Aneurysm Growth Rate in the Spanish Population. [PDF]
Peypoch O +17 more
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PD-L1 mRNA expression correlates with tumor growth rate in giant cell tumor of bone: a volumetric MRI analysis. [PDF]
Lee Y, Choi JY, Kim MJ, Seo SW.
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Growth rate dispersion by initial growth rate distributions and growth rate fluctuations
AIChE Journal, 1987AbstractTwo distinctly different mechanisms that lead to growth rate dispersion have been observed experimentally. One of the mechanisms involves an initial growth rate distribution among nuclei, while the other allows crystal growth rates to fluctuate. The model formulated in the present work includes both phenomena.
R. C. Zumstein, R. W. Rousseau
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