Results 231 to 240 of about 9,477,034 (297)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Thoracic Aortic Aneurysm Growth Rates and Predicting Factors: A Systematic Review and Meta-Analysis. [PDF]

J Am Heart Assoc
Henry M, Campello Jorge CA, van Bakel PAJ, Knauer HA, MacEachern M, van Herwaarden JA, Teixidó-Tura G, Evangelista A, Jeremy RW, Figueroa CA, Patel HJ, Hofmann Bowman M, Eagle K, Burris NS.   +13 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Growth rates in non-syndromic aneurysms of the ascending aorta: a systematic review. [PDF]

Neth Heart J
Cozijnsen L, Adriaans BP, Schermer TR, Groenink M, Schalla S, Bekkers SCAM.   +5 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Metabolomic Profiling of Serum Reveals Energy Metabolism Differences in Nellore Bulls with Divergent Growth Rates during Feedlot Finishing. [PDF]

ACS Omega
S Moreira JB, Ribeiro RV, Cônsolo NRB, Ribeiro GH, Colnago LA, Torres RNS, Machado Neto OR, Curi RA, Chardulo LAL, Baldassini WA.   +9 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Altered expression of metabolic pathways and immune-related genes revealed by RNA sequencing and metabolomic analysis in meat-type chickens with different growth rates. [PDF]

Poult Sci
Ishihara S, Shimamoto S, Fujimura S, Kamimura M, Ijiri D.   +4 more
europepmc   +1 more source

Claw growth rates in a subset of adult, indoor, domestic cats (Felis catus). [PDF]

Vet Dermatol
Contreras ET, Bruner K, Hegwer C, Simpson A.   +3 more
europepmc   +1 more source

A Unified Equation for Predicting Crack Growth in Rubber Composites Across All Crack Growth Rates. [PDF]

Polymers (Basel)
Duncan AM, Akutagawa K, Papageorgiou DG, Ramier JL, Busfield JJC.   +4 more
europepmc   +1 more source