Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Twice-spraying plant growth regulator EDAH stage-regulates maize plant morphology: a novel strategy for enhancing stalk lodging resistance. [PDF]
Liu F +9 more
europepmc +1 more source
Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity. [PDF]
Duregotti E +12 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The Plant Growth Regulator Forchlorfenuron (KT-30) Drives Atherosclerosis Progression via Lipid Homeostasis Disruption: Evidence from ApoE-Deficient Mice. [PDF]
Chen CH +6 more
europepmc +1 more source
Guvermectin, a novel plant growth regulator, can promote the growth and high temperature tolerance of maize. [PDF]
Zhang B +10 more
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Biological agents and plant growth regulator promote rice growth and regenerative capacity. [PDF]
Zhou H, Liu L, Zhou J, He A, Wu Z.
europepmc +1 more source
The Role of N-Glycosylation in the Intracellular Trafficking and Functionality of Neuronal Growth Regulator 1. [PDF]
Sim G, Jeong M, Seo H, Kim J, Lee S.
europepmc +1 more source

