Results 81 to 90 of about 5,905,925 (280)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The fungicide pyraclostrobin affects gene expression by altering the DNA methylation pattern in Magnaporthe oryzae

Frontiers in Plant Science
IntroductionRice blast disease caused by Magnaporthe oryzae has long been the main cause of rice (Oryza sativa L.) yield reduction worldwide. The quinone external inhibitor pyraclostrobin is widely used as a fungicide to effectively control the spread of
Shumei Fang, Shumei Fang, Hanxin Wang, Kaihua Qiu, Yuanyuan Pang, Chen Li, Xilong Liang   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The miR164e–NAC32 module orchestrates maize plant height via post-translational regulation of DELLA protein stability

Plant Communications
Optimization of plant architecture requires precise regulation of internode elongation; however, the post-translational mechanisms that integrate microRNA and phytohormone signaling remain poorly understood. Here, we describe a hierarchical miR164e–NAC32–
Chuanxi Peng, Xi Zhao, Jinzhong Xiao, Xingyu Zhong, Limei Chen, Yan He, Zhaohu Li, Yuyi Zhou, Liusheng Duan   +8 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Leaf ethylene and auxin act as core factors in the regulation of temperature on thidiazuron-induced cotton defoliation

Industrial Crops and Products
The defoliant thidiazuron is applied worldwide to enhance the fiber quality of machine-harvested cotton, and its efficiency is profoundly regulated by temperature. However, little is known about how the temperature after defoliant application affects the
Keke Yu, Zhenwang Zhang, Zexin Wei, Kexin Li, Xiyu Jia, Mingfeng Yang, Jianxin Dong, Mingwei Du, Xiaoli Tian, Zhaohu Li   +9 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Regulating sink-source ratio optimizes cotton defoliation efficiency during the early-to-mid flowering and boll stages

Industrial Crops and Products
The sink-source relationship significantly influences chemical defoliation in cotton. However, studies on the effects of sink-source manipulations at different phenological stages remain limited.
Zhenwang Zhang, Kexin Li, Jiaqi Zhang, Qinghua Liao, Yukun Wang, Xiaocheng Yuan, Keke Yu, Mingfeng Yang, Guodong Chen, Sumei Wan, Shanwei Lou, Fangjun Li, Mingwei Du, Xiaoli Tian, Zhaohu Li   +14 more
doaj   +1 more source

Regulation of Growth [PDF]

Nature, 1965
Adaptive Growth By Prof. Richard J. Goss. Pp. 360. (London: Logos Press, Ltd., in association with Elek Books, Ltd. Distributed by Academic Press, London and New York, 1964.) 70s.
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source