Results 71 to 80 of about 701,195 (269)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Regulating sink-source ratio optimizes cotton defoliation efficiency during the early-to-mid flowering and boll stages

Industrial Crops and Products
The sink-source relationship significantly influences chemical defoliation in cotton. However, studies on the effects of sink-source manipulations at different phenological stages remain limited.
Zhenwang Zhang, Kexin Li, Jiaqi Zhang, Qinghua Liao, Yukun Wang, Xiaocheng Yuan, Keke Yu, Mingfeng Yang, Guodong Chen, Sumei Wan, Shanwei Lou, Fangjun Li, Mingwei Du, Xiaoli Tian, Zhaohu Li   +14 more
doaj   +1 more source

Regulation of Growth [PDF]

Nature, 1965
Adaptive Growth By Prof. Richard J. Goss. Pp. 360. (London: Logos Press, Ltd., in association with Elek Books, Ltd. Distributed by Academic Press, London and New York, 1964.) 70s.
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Sink Strength Governs Yield Ceiling in High-Yield Cotton: Compensation Effects of Source–Sink Damage and Reproductive Stage Regulation

Agronomy
Under refined management, high-yield cotton fields are approaching their maximum output. However, how to break this yield upper limit, specifically the source–sink relationship is still inadequately researched.
Zhenwang Zhang, Kexin Li, Qinghua Liao, Zhijie Shi, Keke Yu, Junqi Zhu, Xiyu Jia, Guodong Chen, Sumei Wan, Shanwei Lou, Mingfeng Yang, Fangjun Li, Xiaoli Tian, Zhaohu Li, Mingwei Du   +14 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Effect of different irrigation and fertilizer coupling on the liquiritin contents of the licorice in Xinjiang arid area

Ecological Indicators
The increasing worldwide demand for traditional herbs has been met by growing cultivated herbs. It is undoubtedly very important to seek a reasonable cultivation mode for the yield, quality and long-term production stability of traditional herbs ...
Abudukeyoumu Abudurezike, Xinghong Liu, Gulimila Aikebaier, Ayixiamu Shawuer, Xiaoli Tian   +4 more
doaj   +1 more source