Results 171 to 180 of about 5,905,925 (280)

Sublethal Effects of the Insect Growth Regulator Novaluron on the Midgut Integrity and Survival of Adult Honey Bee <i>Apis mellifera</i> Workers. [PDF]

open access: yesACS Environ Au
Soares de Oliveira M   +7 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

<i>LvSlc12A2</i> Is a Negative Growth Regulator in Whiteleg Shrimp, <i>Litopenaeus vannamei</i>. [PDF]

open access: yesAnimals (Basel)
Niu P   +10 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Flumetralin based plant growth regulator used in tobacco cultivation induces immune and cytotoxicity in vitro. [PDF]

open access: yesToxicol Res (Camb)
Conte AM   +11 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy