Results 51 to 60 of about 5,785,845 (286)

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster [PDF]

, 2009
Background: Outcomes of lifespan studies in model organisms are particularly susceptible to variations in technical procedures. This is especially true of dietary restriction, which is implemented in many different ways among laboratories.
Linda Partridge, Partridge, L., Wong, Richard, Timothy M Bass, Partridge Linda, Grandison, R.C., Richard Wong, Wong, R., Tanimoto, H., Richard C Grandison, Bass, TM, Matthew D W Piper, Piper, M.D.W., Grandison, RC, Grandison, Richard C., Partridge, Linda, Wong, R, Bass Timothy M., Piper, MDW, Piper Matthew D. W., Partridge, L, Grandison Richard C., Bass, Timothy M., Piper, M. D W, Wong Richard, Bass, T.M.   +25 more
core   +2 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Ultrasound evidence of early fetal growth restriction after maternal malaria infection. [PDF]

, 2012
BACKGROUND: Intermittent preventive treatment (IPT), the main strategy to prevent malaria and reduce anaemia and low birthweight, focuses on the second half of pregnancy. However, intrauterine growth restriction may occur earlier in pregnancy. The aim of
Papageorghiou Aris T., Marcus J. Rijken (170994), Wiladphaingern Jacher, Pimanpanarak Mupawjay, Pimanpanarak, M, François Nosten (17237), Kiricharoen, S, Nosten François, Dwell Saw Lu Mu, Jacher Wiladphaingern, Suporn Kiricharoen (185368), Kennedy, SH, Mupawjay Pimanpanarak, Supan Thiptharakun, Stephen H Kennedy, Aris T. Papageorghiou (185366), Jacher Wiladphaingern (171011), Papageorghiou, Aris, Wiladphaingern, J, Rijken, MJ, Nosten, F, Stephen H. Kennedy (185374), Dwell, SL, François Nosten, Rijken Marcus J., Suporn Kiricharoen, Rose McGready, Thiptharakun Supan, McGready, R, Saw Lu Mu Dwell, Thiptharakun, S, Kennedy Stephen H., Supan Thiptharakun (185367), Aris T Papageorghiou, Mupawjay Pimanpanarak (185371), Saw Lu Mu Dwell (185369), Nosten, Francois, Kiricharoen Suporn, Papageorghiou, AT, Kennedy, Stephen, Marcus J Rijken, McGready Rose, Rose McGready (17231)   +42 more
core   +1 more source

Provision of combined antiretroviral therapy in HIV-positive pregnant women and the increased risk of apoptosis-related intra-uterine growth restriction

HIV & AIDS Review. International Journal of HIV-Related Problems, 2019
Human immunodeficiency virus (HIV) infection during pregnancy is still a major problem worldwide, especially in developing countries. Although administration of anti-retroviral drugs has succeeded in reducing mother-to-child transmission, poor obstetric ...
Artana Putra IW, Ketut Suwiyoga
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Enhancing the utility of placental pathology reports for clinical use

Pregnancy
Obstetric training programs typically offer limited formal education on placental pathology; yet, in practice, obstetric providers are expected to incorporate placental pathology findings into the overall evaluation of obstetric complications.
Janelle Santos, Linda M. Szymanski, Regan N. Theiler, Andrew P. Norgan, Elizabeth Ann L. Enninga, Molly Mcduffie, Lainee A. Bulawa‐Regner, E. Heidi Cheek‐Norgan, Julie A. Lamppa, Myra Wick   +9 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source