Results 121 to 130 of about 7,801,024 (332)

Growth Rings in the Stem of Thuja orientalis L.

open access: yesInternational Journal of Horticultural Science, 2000
During the winter dormancy period of 1998-99, the differentiation process of xylem and the formation of annual and pseudo-annual growth rings was studied in sections of the central stem of Thuja orientalis of different age (1-14 year old), starting from ...
G. Schmidt, Gy. Végvári
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Wood density variations of Norway spruce (Picea abies (L.) Karst.) under contrasting climate conditions in southwestern Germany

open access: yesAnnals of Forest Research, 2013
We analyzed inter-annual variations in ring width and maximum wood density of Norway spruce (Picea abies (L.) Karst.) at different altitudes in Baden-Württemberg, southwestern Germany, to determine the climate response of these parameters under ...
Marieke van der Maaten-Theunissen   +2 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Reconstructing the temperature degree of the warm seasons through Quercus persica tree rings in Zagros forests Dena region [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2015
Trees can record long-term effects of climate variables. Using dendroclimatology knowledge, we can reconstruct such variables especially for areas which have short-term climatic data.
Hossein zarean
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Macroscopic Anatomy as a Strategy for Recognizing Commercial Wood from the Brazilian Amazon

open access: yesBioResources
Wood anatomical characterization is a key method for species identification and for combating illegal logging. This study aimed to provide a detailed macroscopic anatomical characterization of twelve wood species from the Brazilian Amazon, supporting ...
Waldelaine R. Hoffmann   +4 more
doaj  

Fossil wood from the Permian-Triassic Beaufort Group of South Africa’s Karoo Basin: Implications for palaeoclimate

open access: yesEarth History and Biodiversity
Tree-growth rings act as high-resolution climate proxies because wood anatomy is directly related to water uptake and tree growth. 190 silicified wood samples representing three taxa from the main Karoo Basin of South Africa were analysed. These samples (
Simoné Kock, Marion K. Bamford
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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