Results 81 to 90 of about 5,401,070 (277)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Instabilities of thin black rings: closing the gap
Journal of High Energy Physics, 2019 We initiate the study of dynamical instabilities of higher-dimensional black holes using the blackfold approach, focusing on asymptotically flat boosted black strings and singly-spinning black rings in D ≥ 5.
Jay Armas, Enrico Parisini
doaj +1 more source
Rate of Growth of Fungus Rings [PDF]
Nature, 1925 IT is well known that on air-photographs of the chalk downland, fungus rings are often very clearly shown. Sometimes they form the most prominent objects on the photograph and their size is considerable. It has been noticed that they are best developed upon land which has not been under plough for a very long time: in fact they seem never to occur well
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Uptake and Transformation of Hexachlorocyclohexane Isomers (HCHs) in Tree Growth Rings at a Contaminated Field Site. [PDF]
Environ Sci Technol, 2023 Liu X, Kümmel S, Trapp S, Richnow HH.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Correction to: 'Age determination in echinoderms: first evidence of annual growth rings in holothuroids' 2022 by Sun et al. [PDF]
Proc Biol Sci, 2022 Sun J, Hamel JF, Gianasi BL, Mercier A.
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Effects of pruning on heartwood formation in Scots pine trees
Journal of Forest Science, 2004 The object of this study was to investigate the effect of pruning on heartwood formation in mature Scots pine (Pinus sylvestris L.) trees. Fifty trees were treated by three different intensive pruning regimes: 42, 60 and 70 percentage of defoliation ...
B. Bergström, R. Gref, A. Ericsson
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source