Results 61 to 70 of about 1,863 (216)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Evolution of unemployment population stocks in Romania [PDF]
Revista Română de Statistică, 2010 Effects of the current crisis on the evolution of the stocks of theunemployed persons in Romania. The present paper is focused on the analysis of general dynamic of the input and output flows in/from unemployment, emphasising the growth of the stocks of ...
Irena MOCANU
doaj
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
The value premium within and across GICS industry sectors in a pre-financial collapse sample
Cogent Economics & Finance, 2015 A portfolio manager employing a top-down/bottom-up method who seeks to capture the value premium long promised in academic literature would want to first determine whether the premium exists across industries and not just observed in firm-specific book ...
Kenneth E. Scislaw
doaj +1 more source
Growth of the harbour porpoise (Phocoena phocoena) in eastern Newfoundland, Canada
NAMMCO Scientific Publications, 2003 Although the stock relationships among harbour porpoise (Phocoena phocoena) in the Northwest Atlantic are unknown, it has been postulated that there are 4 local populations: Bay of Fundy/Gulf of Maine, Gulf of St.
S F Richardson, G B Stenson, C Hood
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Stock Market Development and Economic Growth [PDF]
, 2008 In the wake of substantial empirical evidence, recent decades have seen economists devoting considerable attention to the study of the interrelationship between financial variables and the processes of real resource allocation. These studies have directed their efforts towards challenging the idea of an existing dichotomy between the real and financial
openaire +2 more sources
Laboratory Animal Research, 2019 In our efforts to understand the systemic features of tumors, the importance of animal models is increasing due to the recent growth in the development of immunotherapy and targeted therapies. This has resulted in increased attention towards tumor animal
Mi Ju Kang +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source