Results 111 to 120 of about 3,655,672 (354)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Bringing Growth Theory "Down to Earth" [PDF]

open access: yes
Explicitly accounting for certain basic physical laws governing the “earth” sector dramatically enriches our ability to explain a high degree of diversity in observed patterns of economic growth. We provide a theoretical explanation of why some countries
Lopez, Ramon E., Stocking, Andrew
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Growing Grounded Theory: Doing my Bit

open access: yesGrounded Theory Review: An International Journal, 2017
In Glaser’s recent book, The Grounded Theory Perspective: Its Origin and Growth (2016), Glaser writes of how he recorded and explicated the grounded theory perspective and disseminated the perspective as the grounded theory general method of research ...
Helen Scott, PhD
doaj  

Form of growth law [PDF]

open access: yesApplied and Computational Mechanics, 2007
Our aim in future is to computer simulate the mechanical stimulated postnatal heart development (normal growth, heart hypertrophy, etc.). We are now interested in the study of the form of growth law [1], which we could use for the simulation.
Tringelová M.
doaj  

Efficiency, Depth and Growth: Quantitative Implications of Finance and Growth Theory [PDF]

open access: yes
We develop a parsimonious finance and endogenous growth model with microeconomic frictions in entrepreneurship and a role for credit constraints. We demonstrate that though an efficiency-growth relation will always exist, the efficiency-depth-growth ...
Alex Trew
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The COVID-19 Pandemic and Economic Growth: Theory and Simulation. [PDF]

open access: yesFront Public Health, 2021
Xiang L, Tang M, Yin Z, Zheng M, Lu S.
europepmc   +1 more source

From Growth Spurts to Sustained Growth: The Nature of Growth and Unified Growth Theory [PDF]

open access: yes
The recent literature on unified growth theory has shed new light on the transition to sustained economic growth. Nevertheless, unified growth theory has not devoted a lot of attention to the nature of economic growth and its impact in the transition ...
Alvaro S. Pereira, Gonçalo Monteiro
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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