Results 111 to 120 of about 1,825,008 (215)
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
ABSTRACT Progressive multifocal “moth‐eaten” osteolysis involving foot and ankle bones after nonoperative treatment of a stable ankle fracture is rare and warrants evaluation for infectious, neoplastic, inflammatory, vascular, and mechanical causes.
Haotian Wu +4 more
wiley +1 more source
Distant view, entrance to garden; As papal architect Ligorio's main project was to design a new casino in the Vatican gardens as an afternoon retreat for the Pope.
Pius IV, Pope, Ligorio, Pirro
core
Temporal Replication and Sampling Efficiency in High‐Frequency Autonomous and Manual eDNA Sampling
Accounting for temporal correlation in eDNA time series can improve the accuracy of ecological inference about the influence of hydrological covariates on eDNA concentration. Further, we found that MCE filters were more efficient than PES filters. ABSTRACT Environmental DNA (eDNA) sampling is a valuable tool for ecological research, but its reliability
Ben C. Augustine +6 more
wiley +1 more source
Adaptation of the population genetics framework to environmental DNA for population‐level inference from mixed and degraded samples. The approach includes allele frequency‐based methods, a Pool‐seq‐based strategy, contributor‐estimation models using targeted nuclear loci, and eDNA‐specific bioinformatics filtering. ABSTRACT Environmental DNA (eDNA) has
Elisa Barreiro‐Docío +3 more
wiley +1 more source
An Optimized Diagnostic Approach for Adults With Suspected Inherited Metabolic Disorders
A multidisciplinary strategy that integrates deep phenotyping with expert genetic interpretation substantially increases the likelihood of reaching a diagnosis in adults suspected of having an IMD. ABSTRACT Inherited metabolic disorders (IMDs) arise from defects in metabolic pathways essential for normal biochemical function.
Machteld M. Oud +12 more
wiley +1 more source
Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa
ABSTRACT Glycogen storage disease type Ia (GSDIa) is a rare, life‐threatening inherited carbohydrate metabolism disorder caused by biallelic pathogenic G6PC gene variants resulting in deficiency of glucose‐6‐phosphatase. DTX401 is an investigational AAV8 vector containing the human G6PC gene. DTX401‐CL301 is a pivotal, phase 3, double‐blind, randomized,
John J. Mitchell +37 more
wiley +1 more source
Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır.ÖZET Anahtar Kelimeler; PMTS, GSD ve Hat Dengelemesi Bu çalışmanın amacı: İşçilik maliyetlerinin arttığı, üretim zamanın, zamanında mamul tesliminin, ön üretim planlamasının ve ön üretim ...
Yardımcı Doçent Doktor Bayram Topal +2 more
core +1 more source
ABSTRACT Long‐chain fatty acid oxidation disorders (LC‐FAOD) are rare inherited defects of mitochondrial β‐oxidation that impair energy generation during fasting or metabolic stress. Clinical manifestations range from neonatal hypoketotic hypoglycemia and cardiomyopathy to hepatopathy, recurrent rhabdomyolysis, and chronic myopathy.
Sarah C. Grünert +37 more
wiley +1 more source
Placental Involvement in Glycogen Storage Disease Type IV
Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder caused by glycogen branching enzyme (GBE) deficiency and resulting in the storage of abnormal glycogen (polyglucosan).
Dertinger, S. +10 more
core +1 more source

