Results 51 to 60 of about 47,665 (225)

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption

Antioxidants, 2021
Cellular oxidants are primarily managed by the thioredoxin reductase-1 (TrxR1)- and glutathione reductase (Gsr)-driven antioxidant systems. In mice having hepatocyte-specific co-disruption of TrxR1 and Gsr (TrxR1/Gsr-null livers), methionine catabolism ...
Colin G. Miller, Jean A. Kundert, Justin R. Prigge, Julie A. Amato, Allison E. Perez, Lucia Coppo, Gabrielle N. Rizzo, Michael P. Kavanaugh, David J. Orlicky, Colin T. Shearn, Edward E. Schmidt   +10 more
doaj   +1 more source

Impact of Moisture Exposure on Thermal Stability and Safety of Solid‐State Batteries

Advanced Energy Materials, EarlyView.
Sulfide‐based solid‐state batteries (SSBs) hold significant potential for next‐generation energy storage, yet their practical deployment is hindered by the moisture sensitivity of sulfide solid electrolytes. This study examines how moisture exposure influences thermo‐electrochemical instability at the material and cell‐level, and underscores the ...
Md Toukir Hasan, Alvaro J. Miguel, Bairav S. Vishnugopi, Abhinanda Sengupta, Avijit Karmakar, Gordon H. Waller, Corey T. Love, Partha P. Mukherjee   +7 more
wiley   +1 more source

An exploration of the utility of GSR in locating events from personal lifelogs for reflection [PDF]

, 2010
Digital personal lifelogs (PLs) enable many artifacts from a person’s life to be automatically stored in a digital archive. These data sets can contain a wealth of potentially valuable information describing events from an individual’s life.
Jones, Gareth J.F., Kelly, Liadh
core  

Context‐Aware Semiautonomous Control for Upper‐Limb Prostheses

Advanced Intelligent Systems, EarlyView.
A semiautonomous prosthetic control strategy integrates electromyographic‐based intention with computer vision‐driven grasp adaptation and wrist orientation. Comparative experiments with functional tasks evaluate performance, usability, and cognitive workload.
Gianmarco Cirelli, Enrica Stefanelli, Roberto Billardello, Christian Tamantini, Silvia Leonelli, Loredana Zollo, Luigi Pietro Cordella, Francesca Cordella   +7 more
wiley   +1 more source

Effects of total cloud cover products on solar radiation estimation based on a radiation transfer model

International Journal of Digital Earth
Global solar radiation (GSR) is the most crucial energy source on Earth, but the effects of cloud on the existing remote sensing inversion of GSR remains uncertain.
Daodao Pan, Xiaojun Xu, Danna Chen
doaj   +1 more source

The Development of ASIC Type GSR Sensor Driven by GHz Pulse Current

Sensors, 2020
The GigaHertz spin rotation (GSR) effect was observed through the excitement of Giga Hertz (GHz) pulse current flowing through amorphous wire. The GSR sensor that was developed provides excellent features that enhanced magnetic sensitivity and sine ...
Yoshinobu Honkura, Shinpei Honkura
doaj   +1 more source

Spatiotemporal variations of global solar radiation: Case Study Egypt

Alexandria Engineering Journal, 2022
The spatio-temporal characteristic of the available global solar radiation (GSR) variability is essential for effective grid integration of photovoltaic (PV) power systems, particularly in developing countries such as Egypt.
M.L. Eladawy, Mostafa Morsy, M.H. Korany, H. Abdel Basset, Mohammed El-Adawy   +4 more
doaj   +1 more source

Near-Maximal Mixing of Scalar Gluonium and Quark Mesons: A Gaussian Sum-Rule Analysis

, 2011
Gaussian QCD sum-rules are ideally suited to the study of mixed states of gluonium (glueballs) and quark ($q\bar q$) mesons because of their capability to resolve widely-separated states of comparable strength. The analysis of the Gaussian QCD sum-rules (
't Hooft, Abramowitz, Albaladejo, Amsler, Bagan, Bagan, Bagan, Belavin, Bertlmann, Binosi, Bordes, Bramon, Burakovsky, Chanowitz, Chen, Close, Close, Collins, D. Harnett, Dominguez, Dosch, Elias, Elias, Fariborz, Fariborz, Feldmann, Feldmann, Forkel, Forkel, Forkel, Harnett, Harnett, Hart, Huang, Jamin, K. Moats, Kisselev, Kisslinger, Kisslinger, Kochelev, Krasnikov, Latorre, Li, Liu, Mennessier, Minkowski, Minkowski, Morningstar, Narison, Narison, Narison, Narison, Narison, Narison, Narison, Nielsen, Novikov, Novikov, Orlandini, Pascual, R.T. Kleiv, Schäefer, Shifman, Shifman, Shuryak, Steele, T.G. Steele, Tarrach, Vaccarino, Yao, Zhang, Zhang   +71 more
core   +1 more source