Results 341 to 350 of about 386,929 (385)

Interaction of liver plasma membranes and GTP with GTP hydrolysis

Biochemical and Biophysical Research Communications, 1973
Abstract [ 14 C]GTP or a metabolic product of GTP binds to liver membranes. Less label was associated with membranes when membranes were incubated with increasing concentrations of carrier GTP; ATP did not displace the label. Chromatography of extracted incubation mixtures of [ 14 C]GTP and membranes revealed that over 96% of the nucleotide was ...
N I, Swislocki, S, Scheinberg, M, Sonenberg   +2 more
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Regulation of GTP biosynthesis

Advances in Enzyme Regulation, 1992
In the regulation of GTP biosynthesis, complex interactions are observed. A major factor is the behavior of the activity of IMPDH, the rate-limiting enzyme of de novo GTP biosynthesis, and the activity of GPRT, the salvage enzyme of guanylate production. The activities of GMP synthase, GMP kinase and nucleoside-diphosphate kinase are also relevant.
G, Weber, H, Nakamura, Y, Natsumeda, T, Szekeres, M, Nagai   +4 more
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GTP-binding proteins in plants

Cellular and Molecular Life Sciences CMLS, 1999
GTP-binding proteins are found in all organisms. They are important switches that cycle between an active and an inactive state, ensuring vectorial flow of information on the expense of guanosine triphosphate (GTP). In this review, we discuss current progress in the molecular characterization and functional analysis of plant genes encoding ...
F, Bischoff, A, Molendijk, C S, Rajendrakumar, K, Palme   +3 more
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Inhibition of erythrocyte transglutaminase by GTP

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1987
The guanine nucleotides GTP, GDP and GMP inhibit the activity of erythrocyte transglutaminase (protein-glutamine:amine gamma-glutamyltransferase, EC 2.3.2.13) in a decreasing order of effectiveness. The inhibition is more apparent at low than at saturating levels of calcium ions and is not due to the chelation of Ca2+, but to an interference with the ...
C M, Bergamini, M, Signorini, L, Poltronieri   +2 more
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Small GTP-Binding Proteins

Physiological Reviews, 2001
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and Ran families.
Y, Takai, T, Sasaki, T, Matozaki
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Stabilization of microtubules by GTP analogues

Biochemical and Biophysical Research Communications, 1990
We recently demonstrated that the nonhydrolyzable analogues of GTP (GMPPCP and GMPPNP) and ATP support the elongation phase of tubulin assembly and are incorporated into the E-site of polymerized tubulin. In this report we studied the stability of microtubules containing GTP analogues by examining length redistributions after shearing at polymer steady
M R, Mejillano, J S, Barton, R H, Himes
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The effect of GTP on benzodiazepine receptors

European Journal of Pharmacology, 1982
GTP decreases the specific binding of [3H]flunitrazepam to cerebral cortical membrane sites. Scatchard analysis data show that GTP does not alter the maximum binding sites (Bmax), but increases the dissociation constant (KD) for [3H]flunitrazepam. GTP also inhibits the specific binding of the benzodiazepine antagonist [3H]CGS-8216. The specific binding
J C, Fong, K, Okada, M, Goldstein
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Purification of Phosphoenolpyruvate Carboxykinase (GTP) by Affinity Chromatography on Agarose-Hydrazide-GTP

Enzyme, 1979
The cytosolic form of phosphoenolpyruvate carboxykinase (GTP; EC 4.1.1.32) from rat liver was purified by a procedure involving affinity chromatography on agarose-hydrazide-GTP. Phosphoenolpyruvate carboxykinase is retained quantitatively by the affinity medium in the presence of manganese and can be specifically eluted by a pulse of GTP.
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GTP-Dependent Membrane Fusion

Annual Review of Cell and Developmental Biology, 2013
Shape changes and topological remodeling of membranes are essential for the identity of organelles and membrane trafficking. Although all cellular membranes have common features, membranes of different organelles create unique environments that support specialized biological functions.
James A, McNew, Holger, Sondermann, Tina, Lee, Mike, Stern, Federica, Brandizzi   +4 more
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GDP/GTP Exchange Proteins for Small GTP-Binding Proteins

1993
There is a superfamily of small GTP-binding proteins in which more than forty members are included (Bourne et al. 1991; Hall 1990; Takai et al. 1992). They exhibit GDP/GTP-binding and GTPase activities and have two interconvertible forms: GDP-bound inactive and GTP-bound active forms (Fig. 1).
Y. Takai, K. Kaibuchi, A. Kikuchi, T. Sasaki   +3 more
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