Results 111 to 120 of about 2,286 (161)

GPCR-Gα13 Involvement in Mitochondrial Function, Oxidative Stress, and Prostate Cancer. [PDF]

Int J Mol Sci
Wu D, Casey PJ.
europepmc   +1 more source

The PAR2 inhibitor I-287 selectively targets Gα_q and Gα_12/13 signaling and has anti-inflammatory effects. [PDF]

Commun Biol, 2020
Avet C, Sturino C, Grastilleur S, Gouill CL, Semache M, Gross F, Gendron L, Bennani Y, Mancini JA, Sayegh CE, Bouvier M.   +10 more
europepmc   +1 more source

Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets [PDF]

Aktories, Amano, Amano, Barrett, Brass, Brass, Buhl, Burridge, Chacko, Chihara, Clark, Clark, Clark, Daniel, Daniel, Dhanasekaran, Dhar, Dong, Essler, Ferrell, Fox, Fox, Fromm, Fujii, Fujita, Gilman, Gohla, Golden, Hart, Hartwig, Hirose, Hooley, Houslay, Hung, Jackson, Johnson, Kimura, Kohama, Kozasa, Laugwitz, Leng, Maeda, Maeda, Majumdar, Matsuoka, Menshikov, Milligan, Morii, Nachmias, Nakai, Nakamura, Narumiya, Negrescu, Negrescu, Offermanns, Offermanns, Offermanns, Offermanns, Ohkubo, Plonk, Rink, Shenker, Siess, Simon, Simpson, Somlyo, Stark, Taniguchi, Uehata, Ushikubi, Wong   +70 more
core   +1 more source

GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions. [PDF]

Nucleic Acids Res
Pándy-Szekeres G, Taracena Herrera LP, Caroli J, Kermani AA, Kulkarni Y, Keserű GM, Gloriam DE.   +6 more
europepmc   +1 more source

Signal profiling of the β₁AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β₁AR and β₂AR. [PDF]

Sci Rep, 2020
Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, Inoue A, Bouvier M, Hébert TE.   +17 more
europepmc   +1 more source

G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling. [PDF]

Mol Cell Biol, 2019
Banu A, Liu KJ, Lax AJ, Grigoriadis AE.
europepmc   +1 more source

When cells respond to light:All you need is LOV [PDF]

, 2020
Van Geel, O.
core  

Melanoma: Pathogenesis and Targeted Therapy. [PDF]

MedComm (2020)
Fu Y, Liu J, Mo Z, Wang B, Deng Y, Jiang Y.   +5 more
europepmc   +1 more source

Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor. [PDF]

Sci Adv
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y.   +19 more
europepmc   +1 more source

Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation. [PDF]

Nat Commun
Czyzyk D, Yan W, Messing S, Gillette W, Tsuji T, Yamaguchi M, Furuzono S, Turner DM, Esposito D, Nissley DV, McCormick F, Simanshu DK.   +11 more
europepmc   +1 more source