Results 81 to 90 of about 330,105 (263)

The Present Situation and Analysis of Dynamic Monitoring and Supervision of Sea Use for Guangzhou Projects in the New Era

open access: yesHaiyang Kaifa yu guanli
Strengthening the dynamic monitoring and supervision of sea use for projects is an important measure to comprehensively implement the new development philosophy and improve the modernization of marine system and capacity for governance in the new era ...
XIAO Hongke, LI Yingying, WANG Li
doaj  

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

open access: yesAdvanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao   +21 more
wiley   +1 more source

Analysis of the influencing factors and spatial heterogeneity characteristics of women’s safety perceptions from street-view images: taking Tianhe District of Guangzhou city as an example

open access: yesJournal of Asian Architecture and Building Engineering
The utilization of streets has proven to have noticeable differences among social groups. However, the actual management of such street usage has generally ignored gender differences, especially the sensitive and vulnerable needs of women, weakening the ...
Bin Li   +3 more
doaj   +1 more source

Guangzhou

open access: yes, 2016
Guangzhou, Canton, Kwangchow, handels- og industriby i Sydkina og hovedstad i Guangdongprovinsen; 12,78 mio. indb. i storbyområdet (2010). Byen har i århundreder haft en absolut særstilling i Kinas udenrigshandel; bl.a. var Perlefloden en fortrinlig transportvej for et stort bagland.
Brødsgaard, Kjeld Erik   +1 more
openaire   +2 more sources

Frustrated Lewis Pairs and Metallic Ni Synergistically Enabled Low‐Temperature Hydrogenolysis of Lignin Models

open access: yesAdvanced Science, EarlyView.
Nickel–aluminum composite oxide (NiAlOx‐300) derived from NiAl layered double hydroxide showed high activity for hydrogenolysis of various lignin models. Especially, hydrogenolysis of benzyl phenyl ether could be efficiently proceeded at 20°C and 1 MPa H2.
Jinpeng Liang   +9 more
wiley   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

open access: yesAdvanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou   +10 more
wiley   +1 more source

Associated Factors of Suboptimal Health Status Among Adolescents in China: A Cross-Sectional Study

open access: yesJournal of Multidisciplinary Healthcare, 2021
Gehendra Mahara,1,* Jiazhi Liang,2,* Zhirong Zhang,3 Qi Ge,1 Jinxin Zhang1 1Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 2Center for Disease Control and Prevention
Mahara G   +4 more
doaj  

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

open access: yesAdvanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang   +10 more
wiley   +1 more source

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