Results 121 to 130 of about 144,757 (372)

An HD-GYP cyclic di-guanosine monophosphate phosphodiesterase with a non-heme diiron-carboxylate active site.

open access: yesBiochemistry, 2013
The intracellular level of the ubiquitous bacterial secondary messenger, cyclic di-(3',5')-guanosine monophosphate (c-di-GMP), represents a balance between its biosynthesis and degradation, the latter via specific phosphodiesterases (PDEs).
K. Miner, K. Klose, D. Kurtz
semanticscholar   +1 more source

Effects of cyclic adenosine 3,5-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. [PDF]

open access: yes, 1982
As a test of the hypothesis that cyclic nucleotides play a role in the regulation of retinomotor movements and disc shedding in the photoreceptor-pigment epithelial complex, we have used an in vitro eyecup preparation that sustains both disc shedding and
Besharse, J, BURNSIDE, Beth, Dunis, D
core   +1 more source

Photoelectrochemical Iron(III) Catalysis for Late‐Stage C─H Fluoroalkylations

open access: yesAngewandte Chemie International Edition, EarlyView.
Efficient electrophotochemical C─H fluoroalkylation of complex bioactive substrates with abundant fluoroalkyl carboxylic acids employing an inexpensive iron(III) catalyst accompanied by hydrogen evolution reaction has been developed. Abstract Chemo‐ and site‐selective functionalization of complex molecules poses a fundamental challenge.
Vladimir Motornov   +8 more
wiley   +1 more source

The genetic code invariance: when Euler and Fibonacci meet [PDF]

open access: yesSymmetry: Culture and Science, Vol.25, No.3, 145-288, 2014, 2014
The number of atoms in the four ribonucleotides uridine monophosphate, cytidine monophosphate, adenine monophosphate and guanine monophosphate is taken as a key parameter. A mathematical relation describing the condensation of the three basic subunits a nucleobase, a ribose and a phosphate group, to form a ribonucleotide, is first obtained from this ...
arxiv  

Modeling oscillatory Microtubule--Polymerization [PDF]

open access: yes, 2002
Polymerization of microtubules is ubiquitous in biological cells and under certain conditions it becomes oscillatory in time. Here simple reaction models are analyzed that capture such oscillations as well as the length distribution of microtubules.
arxiv   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

Salidroside Attenuates Hydrogen Peroxide-Induced Cell Damage Through a cAMP-Dependent Pathway

open access: yesMolecules, 2011
Salidroside, a major component of Rhodiola rosea L., has shown various pharmacological functions, including antioxidant effects, but the signal transduction pathway of its antioxidant effects is not very clear.
Xuming Deng   +6 more
doaj   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

Ca2+-dependent changes in cyclic GMP levels are not correlated with opening and closing of the light-dependent permeability of toad photoreceptors. [PDF]

open access: yes, 1982
We have measured the levels of 3',5'-guanosine monophosphate (cyclic GMP) in isolated retinas from toad to investigate their correlation to the opening and closing of the light-dependent permeability of photoreceptors. When Ca2+-induced changes in cyclic
Fain, GL, Woodruff, ML
core  

Mouse versus Rat: Profound Differences in Meiotic Regulation at the Level of the Isolated Oocyte [PDF]

open access: yes, 2011
Cumulus cell-enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats (25–27 days old) with 12.5 IU of equine chorionic gonadotropin, and exposed ...
Biggers   +61 more
core   +2 more sources

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