Results 301 to 310 of about 162,062 (330)
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Neurosurgery, 1999
OBJECTIVE Preliminary studies have demonstrated that the Ras family and related guanosine triphosphate-dependent proteins are overactivated in malignant gliomas and that inhibition of the activation of such proteins, by blockade of their post ...
I. Pollack +4 more
semanticscholar +1 more source
OBJECTIVE Preliminary studies have demonstrated that the Ras family and related guanosine triphosphate-dependent proteins are overactivated in malignant gliomas and that inhibition of the activation of such proteins, by blockade of their post ...
I. Pollack +4 more
semanticscholar +1 more source
Light-induced phosphorylation of rod outer segments by guanosine triphosphate
Biochemical and Biophysical Research Communications, 1975Abstract Significant GTP-dependent protein kinase activity is present in isolated photoreceptors of the retina. No transfer of the γ- 32 P group from GTP-γ- 32 P to ATP was detected. Although no stimulation of GTP-kinase activity by cyclic GMP or cyclic AMP was observed, exposure of dark-adapted photoreceptors to light resulted in a 46-fold increase ...
Gopal Krishna +2 more
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Role of guanosine triphosphate in ferric ion-linked Fenton chemistry.
Radiation Research, 1996We measured the production of reactive hydroxyl radical (OH.) by Fe2+ itself or complexed with nucleotide triphosphates or tripolyphosphate (TPP). Coumarin-3-carboxylic acid (3-CCA) reacts with the OH.
J. Biaglow +5 more
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Neonatal hyperphenylalaninemia presumably caused by guanosine triphosphate-cyclohydrolase deficiency
The Journal of Pediatrics, 1985C'est la recherche systematique des pteridines dans les urines qui a permis de suspecter le deficit en GTP-cyclohydrolase, 1ere etape de la synthese de la tetrahydrobiopterine (BH 4 ) chez un bebe hyperphenylalaninemique (HPA). Le deficit en BH 4 , variante rare de l'HPA, differe de la PKU classique par le caractere evolutif de l'atteinte neurologique ...
Marie-Madeleine Roger +6 more
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Location of the Guanosine Triphosphate (GTP) Hydrolysis Site in Microtubulesa
Annals of the New York Academy of Sciences, 1986The rate for GTP hydrolysis remains approximately constant during microtubule assembly from microtubular protein. This indicates that GTP hydrolysis does not accompany tubulin-GTP subunit addition to microtubule ends. We suggest that GTP, within tubulin-GTP subunits that are incorporated into microtubules, is hydrolyzed predominantly at one or both ...
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Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export.
Science, 1997A leucine-rich nuclear export signal (NES) allows rapid export of proteins from cell nuclei. Microinjection studies revealed a role for the guanosine triphosphatase (GTPase) Ran in NES-mediated export.
S. Richards +2 more
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In vitro nonenzymatic glycation of guanosine 5′-triphosphate by dihydroxyacetone phosphate
Analytical and Bioanalytical Chemistry, 2008Dihydroxyacetone phosphate (DHAP) is a glycolytic intermediate that has been found to be significantly elevated in the erythrocytes of diabetic patients and patients with triosephosphate isomerase deficiency. DHAP spontaneously breaks down to methylglyoxal, a potent glycating agent that reacts with proteins and nucleic acids in vivo to form advanced ...
Udayan Dutta +4 more
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Requirement for guanosine triphosphate in the activation of adenylate cyclase by cholera toxin
Journal of Supramolecular Structure, 1979AbstractThe activation of adenylate cyclase in lysed pigeon erythrocytes requires, among several cofactors, a nucleotide which may be ATP, GTP, or many other triphosphates. However, after removal of endogenous nucleotides by gel filtration or by adsorption onto charcoal the requirement can be met only by GTP, or an analog of GTP.
Enomoto K, Gill Dm
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Biochemistry, 1998
The dynamic properties of the alpha-subunit of bovine transducin (Galphat) were studied using molecular dynamics simulations and essential dynamics analyses.
L. Mello, D. V. van Aalten, J. Findlay
semanticscholar +1 more source
The dynamic properties of the alpha-subunit of bovine transducin (Galphat) were studied using molecular dynamics simulations and essential dynamics analyses.
L. Mello, D. V. van Aalten, J. Findlay
semanticscholar +1 more source
Guanosine-5?-triphosphate hydrolysis and tubulin polymerization
Molecular and Cellular Biochemistry, 1982GTP hydrolysis associated with polymerization is a distinctive feature of microtubule assembly. This reaction may be fundamentally linked to the dynamic properties of microtubules in vivo. Kinetic analysis of the connection between microtubule assembly and associated GTP hydrolysis indicates that these two events are kinetically uncoupled, GTP ...
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