Results 311 to 320 of about 159,662 (351)

Structural and guanosine triphosphate/diphosphate requirements for transit peptide recognition by the cytosolic domain of the chloroplast outer envelope receptor, Toc34.

Biochemistry, 2002
Toc34 is a transmembrane protein located in the outer envelope membrane of chloroplasts and involved in transit peptide recognition. The cytosolic region of Toc34 reveals 34% alpha-helical and 26% beta-strand structure and is stabilized by intramolecular
Enrico Schleiff, Jrgen Soll, N. Sveshnikova, R. Tien, Sarah J. Wright, C. Dabney-Smith, C. Subramanian, Barry D. Bruce   +7 more
semanticscholar   +1 more source

Preparative method of obtaining guanosine 5′-triphosphate

Chemistry of Natural Compounds, 1965
1. The kinetics of the formation of guanosine 5′-triphosphate, 5′-diphosphate, and 5′-monophosphate in the reaction of the morpholide of guanosine 5′-monophosphate with bis-(tributylammonium) pyrophosphate in pyridine at 27° has been recorded. 2. In the reaction of the morpholide of guanosine 5′-monophosphate with bis-(tributylammonium) pyrophosphate ...
T. S. Lomakina, N. I. Grineva
openaire   +2 more sources

Evidence for Guanosine Triphosphate—Binding Proteins in Trypanosoma cruzi

The American Journal of Tropical Medicine and Hygiene, 1994
The transformation of the parasite Trypanosoma cruzi from the blood-borne trypomastigote to the intracellular amastigote constitutes a key clinical feature in the pathophysiology of Chagas' disease. That this transition occurs without change in the integrity of the plasma membrane of the parasite suggests the presence of biochemical structures, i.e ...
Huan Huang, Oz Hs, Stephen A. Morris, M Wittner, H. B. Tanowitz, John P. Bilezikian   +5 more
openaire   +3 more sources

Microtubule dynamics modulated by guanosine triphosphate hydrolysis activity of beta-tubulin.

Science, 1994
Microtubule dynamic instability underlies many cellular functions, including spindle morphogenesis and chromosome movement. The role of guanosine triphosphate (GTP) hydrolysis in dynamic instability was investigated by introduction of four mutations into
Ashley S. Davis, Carleton R. Sage, Cynthia A. Dougherty, Kevin W. Farrell   +3 more
semanticscholar   +1 more source

Guanosine triphosphate activation of brain adenylate cyclase: enhancement by long-term antidepressant treatment.

Science, 1983
Activation of adenylate cyclase by a stable guanosine 5'-triphosphate analog was augmented in brain membrane preparations from rats treated on a long-term basis with tricyclic antidepressants or electroconvulsive shock.
D. Menkes, M. Rasenick, M. Wheeler, M. Bitensky   +3 more
semanticscholar   +1 more source

The effect of guanosine 5′-triphosphate analogues on protein synthesis

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971
Abstract Four GTP analogues, 6-mercaptoguanosine 5′-triphosphate (I), N2-methylguanosine 5′-triphosphate (II), N2-dimethylguanosine 5′-triphosphate (III) and 8-bromoguanosine 5′-triphosphate, (IV) were synthesized chemically and tested for their ability to replace GTP in the cell-free amino acid incorporation system of Escherichia coli.
Morio Ikehara, Eiko Ohtsuka, Hitoshi Uno, Shintaro Oyabu   +3 more
openaire   +3 more sources

Direct incorporation of guanosine 5-diphosphate into microtubules without guanosine 5'-triphosphate hydrolysis

Biochemistry, 1986
Using highly purified calf brain tubulin bearing [8-14C]guanosine 5'-diphosphate (GDP) in the exchangeable nucleotide site and heat-treated microtubule-associated proteins (both components containing negligible amounts of nucleoside diphosphate kinase and nonspecific phosphatase activities), we have found that a significant proportion of exchangeable ...
Janendra K. Batra, Chii M. Lin, Ernest Hamel   +2 more
openaire   +3 more sources

Inhibition of Ras and related guanosine triphosphate-dependent proteins as a therapeutic strategy for blocking malignant glioma growth: II--preclinical studies in a nude mouse model.

Neurosurgery, 1999
OBJECTIVE Preliminary studies have demonstrated that the Ras family and related guanosine triphosphate-dependent proteins are overactivated in malignant gliomas and that inhibition of the activation of such proteins, by blockade of their post ...
I. Pollack, M. Bredel, M. Erff, A. Hamilton, S. Sebti   +4 more
semanticscholar   +1 more source

Adenosine Triphosphate and Guanosine Triphosphate Determinations in Intertidal Sediments

1979
Measurements were made of the spatial distributions of adenosine triphosphate (ATP) on a variety of sandy beaches. Samples were collected during ebb flow and extracted in the field using cold sulfuric acid and ethylenediamine tetraacetate (EDTA); the neutralized extracts were immediately frozen for subsequent analyses.
openaire   +2 more sources

Structural and Functional Relationships of Guanosine Triphosphate Binding Proteins

1988
Information available at present documents the existence of three well-defined classes of guanine nucleotide binding proteins functioning as signal transducers: Gs and Gi which stimulate and inhibit adenylate cyclase, respectively, and transducin which transmits and amplifies the signal from light-activated rhodopsin to cGMP-dependent phosphodiesterase
Ernst J.M. Helmreich, Thomas Pfeuffer
openaire   +3 more sources