Results 131 to 140 of about 2,686,370 (343)
“Ne bis in idem” Principle, Double Jeopardy Guarantee and Their Application in the Fields of Punishment and Sanctioning: Differences, Merits and Demerits [PDF]
Societas et Iurisprudentia, 2017 The authors of the presented paper analyse the case law of the European Court of Human Rights in the field of the “ne bis in idem” guarantee. They focus in particular on the approach of this court to the issue of liability for crimes and payment offenses.
Ľubica Masárová, Michal Maslen
doaj
On Universal Approximation by Neural Networks with Uniform Guarantees on\n Approximation of Infinite Dimensional Maps [PDF]
, 2019 William H. Guss, Ruslan Salakhutdinov
openalex +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Bit Complexity of Computing Solutions for Symmetric Hyperbolic Systems\n of PDEs with Guaranteed Precision [PDF]
, 2018 Svetlana Selivanova, Victor Selivanov
openalex +1 more source
Can Free Trade Guarantee Gains from Trade? [PDF]
Static and dynamic gains from trade are the reasons why countries embark on the path of free trade, expecting this to promote industrialization and development.
Cruz, Moritz
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source