Results 131 to 140 of about 3,940,943 (324)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Politics of Social Policy Implementation: The Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) and Uneven Development in India

open access: yesThe Journal of Indian and Asian Studies
Since the onset of the twenty-first century, India has initiated various social welfare programs to provide social protection for the people who have been marginalized from the formal social safety net.
JONGWAN BAIK
doaj   +1 more source

Regulatory Compliance and Web Accessibility of UK Parliament Sites [PDF]

open access: yes, 2009
This research seeks to review whether web accessibility and disability laws lead to strong compliance among UK e-government web sites. This study samples 130 sites of the UK members of Parliament using an online accessibility testing tool and determines ...
Kuzma, Joanne
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

SBA Veterans Assistance Programs: An Analysis of Contemporary Issues [PDF]

open access: yes, 2019
[Excerpt] This report opens with an examination of the economic circumstances of veteran-owned businesses drawn from the Bureau of the Census’s 2012 Survey of Business Owners (SBO).
Dilger, Robert Jay, Lowry, Sean
core   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Leading Lady: Sallie Mae and the Origins of Today's Student Loan Controversy [PDF]

open access: yes, 2007
Over the past 40 years, the student loan industry has evolved from a relatively small, government-sponsored program into an $85 billion a year industry with thousands of lenders and industry-related companies.
Erin Dillon
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Euskal osasun-sistema juridikoaren kontratu-programa

open access: yesRevista Vasca de Administración Pública, 2007
The Health Planning Act of Euskadi lays down that the Autonomous Community of Euskadi shall guarantee a suitable allocation of public resources in order to stand up to health care needs by planning a rationalization of resources.
José Antonio Arratibel Arrondo
doaj   +1 more source

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