Results 41 to 50 of about 1,810 (157)

Identification of Potential Genetic Biomarkers and Target Genes of Peri‐Implantitis Using Bioinformatics Tools

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Objectives. To investigate potential genetic biomarkers of peri‐implantitis and target genes for the therapy of peri‐implantitis by bioinformatics analysis of publicly available data. Methods. The GSE33774 microarray dataset was downloaded from the Gene Expression Omnibus (GEO).
Xiaogen Zhang, Zhifa Wang, Li Hu, Xiaoqing Shen, Chundong Liu, Rafael Scaf De Molon   +5 more
wiley   +1 more source

Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation. [PDF]

PLoS ONE, 2012
GABA type-A receptors are essential for fast inhibitory neurotransmission and are critical in brain function. Surprisingly, expression of receptor subunits is highly variable among individuals, but the cause and impact of this fluctuation remains unknown.
Megan K Mulligan, Xusheng Wang, Adrienne L Adler, Khyobeni Mozhui, Lu Lu, Robert W Williams   +5 more
doaj   +1 more source

VEGF Contributes to Mesenchymal Stem Cell‐Mediated Reversion of Nor1‐Dependent Hypertrophy in iPS Cell‐Derived Cardiomyocytes

Stem Cells International, Volume 2021, Issue 1, 2021., 2021
Myocardial hypertrophy is present in many heart diseases, representing a strong predictor of adverse cardiovascular outcomes. Regarding therapeutic intervention, mesenchymal stem cells (MSCs) have been suggested to significantly reduce cardiac hypertrophy and progression to heart failure.
Denise Philipp, Michelle Holthaus, Vida Basoah, Kurt Pfannkuche, Laura Suhr, Thorsten Wahlers, Adnana Paunel-Görgülü, Kenichi Tamama   +7 more
wiley   +1 more source

Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells [PDF]

, 2018
Foods rich in polyphenols such as procyanidins (PC) have been proposed to have anti-inflammatory properties, and we have previously reported inhibition of lipopolysaccharide (LPS)-induced inflammatory cytokine secretion in human dendritic cells (DCs) by ...
Bak, Bidani, Bitzer, Chang, Choy, Conboy, Da Silva, Denis, Farache, Gea, Gentile, Giordano, Jang, Kambayashi, Kimura, Madrigal-Carballo, Manach, Martinez-Micaelo, Martinez-Micaelo, Midttun, Miyake, Mueller-Harvey, Nathan, O'Neill, Oz, Rahman, Reed, Rios, Schulz, Scott, Stamenkovic, Sung, Thomas, Tusher, Williams, Williams, Yu   +36 more
core   +1 more source

Association between Genetic Variants of Nitric Oxide/cGMP Pathway and Susceptibility to Hypertension in Kermanshah Province

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Hypertension is a global health challenge due to its high prevalence and increased risk of cardiovascular disease. It is a multifactorial disease in which both genetic and environmental factors are involved.
Parham Nejati, Saba Naseri, Maryam Eini, Reza Alibakhshi, Sousan Mahmoudi, Lida Haghnazari, Nazanin Jalilian   +6 more
doaj  

Mechanism of tanshinones and phenolic acids from Danshen in the treatment of coronary heart disease based on co-expression network

BMC Complementary Medicine and Therapies, 2020
Background The tanshinones and phenolic acids in Salvia miltiorrhiza (also named Danshen) have been confirmed for the treatment of coronary heart disease (CHD), but the action mechanisms remain elusive.
Dongxue Wu, Mengqi Huo, Xi Chen, Yanling Zhang, Yanjiang Qiao   +4 more
doaj   +1 more source

Profiling age-related epigenetic markers of stomach adenocarcinoma in young and old subjects [PDF]

, 2015
The purpose of our study is to identify epigenetic markers that are differently expressed in the stomach adenocarcinoma (STAD) condition. Based on data from The Cancer Genome Atlas (TCGA), we were able to detect an age-related difference in methylation ...
Bhak, Jong Hwa, Chung, Hae Young, Im, Eunok, Jeong, Hyoung Oh, Kim, Byoung-Chul, Kim, Chul-Hong, Kim, Dae Hyun, Kim, Nam Deuk, Lee, Eun Kyeong, Lee, Sunghoon, Park, Daeui, Yu, Byung Pal   +11 more
core   +2 more sources

Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Scientific Reports, 2017
Hypertension is a dominating risk factor for cardiovascular disease. To characterize the genomic response to hypertension, we administered vehicle or angiotensin II to mice and performed gene expression analyses.
Catarina Rippe, Baoyi Zhu, Katarzyna K. Krawczyk, Ed. Van Bavel, Sebastian Albinsson, Jonas Sjölund, Erik N. T. P. Bakker, Karl Swärd   +7 more
doaj   +1 more source

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND) [PDF]

, 2015
Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease (CKD) in the industrialized world and accounts for much of the excess mortality in patients with diabetes mellitus. Approximately 45% of U.S.
Abboud, Hanna E., Adler, Sharon G., Best, Lyle G., Bowden, Donald W., Burlock, Allison, Chen, Yii-Der Ida, Cole, Shelley A., Comeau, Mary E., Curtis, Jeffrey M., DIvers, Jasmin, Drechsler, Christiane, Duggirala, Ravi, Elston, Robert C., Family Investigation of Nephropathy and Diabetes (FIND) Research Group, Freedman, Barry I., Guo, Xiuqing, Hanson, Robert L., Hoffmann, Michael M., Howard, Barbara V., Huang, Huateng, Igo, Robert P., Jr., Ipp, Eli, Iyengar, Sudha K., Kao, W. H. Linda, Keller, Benjamin J., Kimmel, Paul L., Klag, Michael J., Knowler, William C., Kohn, Orly F., Kretzler, Matthias, Langefeld, Carl D., Leak, Tennille S., Leehey, David J., Li, Man, Malhotra, Alka, Marz, Winfried, Nair, Viji, Nelson, Robert G., Nicholas, Susanne B., O\u27Brien, Stephen J., Pahl, Madeleine V., Parekh, Rulan S., Pezzolesi, Marcus G., Rasooly, Rebekah S., Rotimi, Charles N., Rotter, Jerome I., Schelling, Jeffrey R., Sedor, John R., Seldin, Michael F., Shah, Vallabh O., Smiles, Adam M., Smith, Michael W., Taylor, Kent D., Thameem, Farook, Thornley-Brown, Denyse P., Truitt, Barbara J., Wanner, Christoph, Weil, E. Jennifer, Winkler, Cheryl, Zager, Philip G.   +59 more
core   +4 more sources

GEN-O-MA project: an Italian network studying clinical course and pathogenic pathways of moyamoya disease—study protocol and preliminary results [PDF]

, 2019
Background: GENetics of mOyaMoyA (GEN-O-MA) project is a multicenter observational study implemented in Italy aimed at creating a network of centers involved in moyamoya angiopathy (MA) care and research and at collecting a large series and bio ...
Acerbi, Francesco, Baracchini, Claudio, Bedini, Gloria, Bersano, Anna, Binelli, Simona, Blecharz, Kinga, Bono, Giorgio, Bruzzone, Maria Grazia, Calloni, Maria Vittoria, Capone, Fioravanti, Capra, Valeria, Caputi, Luigi, Caria, Filomena, Carolei, Antonio, Caso, Valeria, Cenzato, Marco, Ciceri, Elisa, Ciusani, Emilio, De Lodovici, Maria Luisa, Dell' Acqua, Maria Luisa, Di Lazzaro, Vincenzo, Di Piero, Vittorio, Esposito, Silvia, Faragò, Giuseppe, Farina, Filippo, Ferroli, Paolo, Franceschetti, Silvana, Fratianni, Alessia, Gioppo, Andrea, Grisoli, Marina, Lanfranconi, Silvia, Lasserve, Elisabeth Tournier, Marzoli, Stefania Bianchi, Nardocci, Nardo, Nava, Sara, null, null, Paciaroni, Maurizio, Pantaleoni, Chiara, Pantoni, Leonardo, Parati, Eugenio Agostino, Pavanello, Marco, Perrone, Patrizia, Pezzini, Alessandro, Prontera, Paolo, Raso, Alessandro, Riva, Daria, Romani, Alfredo, Sacco, Simona, Saletti, Veronica, Sanguigni, Sandro, Sarti, Cristina, Sebastiano, Davide Rossi, Toni, Danilo, Toscano, Massimiliano, Vajkoczy, Peter, Zedde, Maria Luisa, Zibordi, Federica, Zini, Andrea   +57 more
core   +1 more source